Visible light-induced photoredox catalyzed C–N coupling of amides with alcohols

A visible-light-mediated method for the construction of N-monoalkylated products from easily available benzamides and benzyl alcohol in the presence of eosin Y has been developed. The reaction proceeded smoothly, for a wide range of derivatives of benzamides and benzyl alcohols, to give the desired...

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Autores principales: Tivari, Shraddha, Singh, Pravin K., Singh, Praveen P., Srivastava, Vishal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730743/
https://www.ncbi.nlm.nih.gov/pubmed/36540212
http://dx.doi.org/10.1039/d2ra07065k
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author Tivari, Shraddha
Singh, Pravin K.
Singh, Praveen P.
Srivastava, Vishal
author_facet Tivari, Shraddha
Singh, Pravin K.
Singh, Praveen P.
Srivastava, Vishal
author_sort Tivari, Shraddha
collection PubMed
description A visible-light-mediated method for the construction of N-monoalkylated products from easily available benzamides and benzyl alcohol in the presence of eosin Y has been developed. The reaction proceeded smoothly, for a wide range of derivatives of benzamides and benzyl alcohols, to give the desired products in good to excellent yields. Biological studies, such as those on drug-likeness and molecular docking, are carried out on the molecules.
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spelling pubmed-97307432022-12-19 Visible light-induced photoredox catalyzed C–N coupling of amides with alcohols Tivari, Shraddha Singh, Pravin K. Singh, Praveen P. Srivastava, Vishal RSC Adv Chemistry A visible-light-mediated method for the construction of N-monoalkylated products from easily available benzamides and benzyl alcohol in the presence of eosin Y has been developed. The reaction proceeded smoothly, for a wide range of derivatives of benzamides and benzyl alcohols, to give the desired products in good to excellent yields. Biological studies, such as those on drug-likeness and molecular docking, are carried out on the molecules. The Royal Society of Chemistry 2022-12-08 /pmc/articles/PMC9730743/ /pubmed/36540212 http://dx.doi.org/10.1039/d2ra07065k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Tivari, Shraddha
Singh, Pravin K.
Singh, Praveen P.
Srivastava, Vishal
Visible light-induced photoredox catalyzed C–N coupling of amides with alcohols
title Visible light-induced photoredox catalyzed C–N coupling of amides with alcohols
title_full Visible light-induced photoredox catalyzed C–N coupling of amides with alcohols
title_fullStr Visible light-induced photoredox catalyzed C–N coupling of amides with alcohols
title_full_unstemmed Visible light-induced photoredox catalyzed C–N coupling of amides with alcohols
title_short Visible light-induced photoredox catalyzed C–N coupling of amides with alcohols
title_sort visible light-induced photoredox catalyzed c–n coupling of amides with alcohols
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730743/
https://www.ncbi.nlm.nih.gov/pubmed/36540212
http://dx.doi.org/10.1039/d2ra07065k
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AT singhpravink visiblelightinducedphotoredoxcatalyzedcncouplingofamideswithalcohols
AT singhpraveenp visiblelightinducedphotoredoxcatalyzedcncouplingofamideswithalcohols
AT srivastavavishal visiblelightinducedphotoredoxcatalyzedcncouplingofamideswithalcohols

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