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Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review

Most patients with advanced gastric cancer were treated with palliative therapy, which had a poor curative effect and a short survival time. In recent years, the clinical research of immune checkpoint inhibitors in advanced gastric cancer has made a breakthrough and has become an important treatment...

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Detalles Bibliográficos
Autores principales: Shen, Jingjing, Wang, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730822/
https://www.ncbi.nlm.nih.gov/pubmed/36505771
http://dx.doi.org/10.3389/fonc.2022.934249
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author Shen, Jingjing
Wang, Zhongming
author_facet Shen, Jingjing
Wang, Zhongming
author_sort Shen, Jingjing
collection PubMed
description Most patients with advanced gastric cancer were treated with palliative therapy, which had a poor curative effect and a short survival time. In recent years, the clinical research of immune checkpoint inhibitors in advanced gastric cancer has made a breakthrough and has become an important treatment for advanced gastric cancer. The modes of immune checkpoint inhibitors in the treatment of advanced gastric cancer include single drug, combined chemotherapy, radiotherapy, and multiple immune drug combination therapy, among which combination therapy shows better clinical efficacy, and a large number of trials are currently exploring more effective combination therapy programs. In this paper, the new clinical research progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer is reviewed, with an emphasis on combination therapy.
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spelling pubmed-97308222022-12-09 Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review Shen, Jingjing Wang, Zhongming Front Oncol Oncology Most patients with advanced gastric cancer were treated with palliative therapy, which had a poor curative effect and a short survival time. In recent years, the clinical research of immune checkpoint inhibitors in advanced gastric cancer has made a breakthrough and has become an important treatment for advanced gastric cancer. The modes of immune checkpoint inhibitors in the treatment of advanced gastric cancer include single drug, combined chemotherapy, radiotherapy, and multiple immune drug combination therapy, among which combination therapy shows better clinical efficacy, and a large number of trials are currently exploring more effective combination therapy programs. In this paper, the new clinical research progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer is reviewed, with an emphasis on combination therapy. Frontiers Media S.A. 2022-11-24 /pmc/articles/PMC9730822/ /pubmed/36505771 http://dx.doi.org/10.3389/fonc.2022.934249 Text en Copyright © 2022 Shen and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Shen, Jingjing
Wang, Zhongming
Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review
title Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review
title_full Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review
title_fullStr Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review
title_full_unstemmed Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review
title_short Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review
title_sort recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: a review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730822/
https://www.ncbi.nlm.nih.gov/pubmed/36505771
http://dx.doi.org/10.3389/fonc.2022.934249
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