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Prevalence of fatty liver and its related factors in children

BACKGROUND: Fatty liver disease is a severe liver condition that affects youngsters. Liver disease in children increases the incidence of liver fibrosis in their adulthood. Due to the importance of this disease and related factors in children, such as diabetes and obesity, our study was conducted to...

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Autores principales: Sadeghian, Mahnaz, Vafadar, Mehdi, Torabi, Ala, Torabi, Sara, Fazel, Mehrshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730962/
https://www.ncbi.nlm.nih.gov/pubmed/36505576
http://dx.doi.org/10.4103/jfmpc.jfmpc_626_22
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author Sadeghian, Mahnaz
Vafadar, Mehdi
Torabi, Ala
Torabi, Sara
Fazel, Mehrshad
author_facet Sadeghian, Mahnaz
Vafadar, Mehdi
Torabi, Ala
Torabi, Sara
Fazel, Mehrshad
author_sort Sadeghian, Mahnaz
collection PubMed
description BACKGROUND: Fatty liver disease is a severe liver condition that affects youngsters. Liver disease in children increases the incidence of liver fibrosis in their adulthood. Due to the importance of this disease and related factors in children, such as diabetes and obesity, our study was conducted to investigate the prevalence of fatty liver in children. MATERIALS AND METHODS: This is a descriptive cross-sectional study done in Ali Asghar Hospital from June 2020 to December 2020. Demographic characteristics and prevalence of fatty liver were assessed. Blood samples were obtained after ten hours of fasting to assess AST, ALT, ALP, and blood glucose levels. Ultrasound was also used to check the health of the liver. Walking to school and exercising were also assessed. Data were analyzed using statistical software. RESULTS: This research included 2526 children, and 37 of them had fatty liver. Fatty liver was more common in children with a BMI greater than 30, as well as metabolic and hypoparathyroid illness (P = 0.02). A significant association was observed between exercise and walking with fatty liver disease (P < 0.05). The majority of the individuals had grade 1 fatty liver (75.5%). Grade 1 fatty liver was seen in 90% of those who did not participate in athletics and 95% of those who did not walk to school. In addition, 94% of patients who exercised for less than ten minutes had grade 1fatty liver. CONCLUSION: Initially, exercise and weight loss had an essential effect on fatty liver disease. In fact, lifestyle changes and prevention of obesity may reduce liver damage.
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spelling pubmed-97309622022-12-09 Prevalence of fatty liver and its related factors in children Sadeghian, Mahnaz Vafadar, Mehdi Torabi, Ala Torabi, Sara Fazel, Mehrshad J Family Med Prim Care Original Article BACKGROUND: Fatty liver disease is a severe liver condition that affects youngsters. Liver disease in children increases the incidence of liver fibrosis in their adulthood. Due to the importance of this disease and related factors in children, such as diabetes and obesity, our study was conducted to investigate the prevalence of fatty liver in children. MATERIALS AND METHODS: This is a descriptive cross-sectional study done in Ali Asghar Hospital from June 2020 to December 2020. Demographic characteristics and prevalence of fatty liver were assessed. Blood samples were obtained after ten hours of fasting to assess AST, ALT, ALP, and blood glucose levels. Ultrasound was also used to check the health of the liver. Walking to school and exercising were also assessed. Data were analyzed using statistical software. RESULTS: This research included 2526 children, and 37 of them had fatty liver. Fatty liver was more common in children with a BMI greater than 30, as well as metabolic and hypoparathyroid illness (P = 0.02). A significant association was observed between exercise and walking with fatty liver disease (P < 0.05). The majority of the individuals had grade 1 fatty liver (75.5%). Grade 1 fatty liver was seen in 90% of those who did not participate in athletics and 95% of those who did not walk to school. In addition, 94% of patients who exercised for less than ten minutes had grade 1fatty liver. CONCLUSION: Initially, exercise and weight loss had an essential effect on fatty liver disease. In fact, lifestyle changes and prevention of obesity may reduce liver damage. Wolters Kluwer - Medknow 2022-09 2022-10-14 /pmc/articles/PMC9730962/ /pubmed/36505576 http://dx.doi.org/10.4103/jfmpc.jfmpc_626_22 Text en Copyright: © 2022 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sadeghian, Mahnaz
Vafadar, Mehdi
Torabi, Ala
Torabi, Sara
Fazel, Mehrshad
Prevalence of fatty liver and its related factors in children
title Prevalence of fatty liver and its related factors in children
title_full Prevalence of fatty liver and its related factors in children
title_fullStr Prevalence of fatty liver and its related factors in children
title_full_unstemmed Prevalence of fatty liver and its related factors in children
title_short Prevalence of fatty liver and its related factors in children
title_sort prevalence of fatty liver and its related factors in children
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730962/
https://www.ncbi.nlm.nih.gov/pubmed/36505576
http://dx.doi.org/10.4103/jfmpc.jfmpc_626_22
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