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Primary screening of cervical cancer by Pap smear in women of reproductive age group

INTRODUCTION: Cancer cervix is a major health problem responsible for causing a higher mortality rate in women worldwide; the exponential increase in such cases can be reduced by early screening of women. The cytology-based cervical screening had a higher success rate in reducing the incidence of ce...

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Autores principales: Mishra, Ruchi, Bisht, Dakshina, Gupta, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731055/
https://www.ncbi.nlm.nih.gov/pubmed/36505559
http://dx.doi.org/10.4103/jfmpc.jfmpc_68_22
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author Mishra, Ruchi
Bisht, Dakshina
Gupta, Manisha
author_facet Mishra, Ruchi
Bisht, Dakshina
Gupta, Manisha
author_sort Mishra, Ruchi
collection PubMed
description INTRODUCTION: Cancer cervix is a major health problem responsible for causing a higher mortality rate in women worldwide; the exponential increase in such cases can be reduced by early screening of women. The cytology-based cervical screening had a higher success rate in reducing the incidence of cervical cancer. The present study aimed to evaluate the use of Pap smear screening to find cytological abnormalities and precancerous lesions. MATERIALS AND METHODS: Sexually active women over 21 years of age were enrolled for the study. A detailed history was taken on the preformed proforma, and all were subjected to vaginal examination. Samples for Pap smear were taken with the help of Ayre spatula and immediately spread over a marked grease-free glass slide and dipped into 95% ethyl alcohol fixative for cytological examination. RESULTS: Most of the abnormality of the epithelial cells found was in the age range of 31–50 years, and most of them were multiparous. 47.92% of the women had a chief complaint of vaginal discharge, an irregular menstrual cycle in 11.07%, and abdominal pain in 7.83%, while 30.41% were asymptomatic. Women found negative for intraepithelial neoplasia were 82.94%, while 13.36% had an inflammatory smear. 0.92% atypical squamous cells of undetermined significance (ASCUS), 2.78% Low-grade squamous intraepithelial lesion (LSIL) were found, no woman had High-grade squamous intraepithelial lesion (HSIL). CONCLUSION: Pap smear is a simple, cost-effective, non-invasive, and easy to perform tool for early detection of precancerous lesions, and it is evident that every woman above the age of 25–30 years must be recommended for cervical screening.
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spelling pubmed-97310552022-12-09 Primary screening of cervical cancer by Pap smear in women of reproductive age group Mishra, Ruchi Bisht, Dakshina Gupta, Manisha J Family Med Prim Care Original Article INTRODUCTION: Cancer cervix is a major health problem responsible for causing a higher mortality rate in women worldwide; the exponential increase in such cases can be reduced by early screening of women. The cytology-based cervical screening had a higher success rate in reducing the incidence of cervical cancer. The present study aimed to evaluate the use of Pap smear screening to find cytological abnormalities and precancerous lesions. MATERIALS AND METHODS: Sexually active women over 21 years of age were enrolled for the study. A detailed history was taken on the preformed proforma, and all were subjected to vaginal examination. Samples for Pap smear were taken with the help of Ayre spatula and immediately spread over a marked grease-free glass slide and dipped into 95% ethyl alcohol fixative for cytological examination. RESULTS: Most of the abnormality of the epithelial cells found was in the age range of 31–50 years, and most of them were multiparous. 47.92% of the women had a chief complaint of vaginal discharge, an irregular menstrual cycle in 11.07%, and abdominal pain in 7.83%, while 30.41% were asymptomatic. Women found negative for intraepithelial neoplasia were 82.94%, while 13.36% had an inflammatory smear. 0.92% atypical squamous cells of undetermined significance (ASCUS), 2.78% Low-grade squamous intraepithelial lesion (LSIL) were found, no woman had High-grade squamous intraepithelial lesion (HSIL). CONCLUSION: Pap smear is a simple, cost-effective, non-invasive, and easy to perform tool for early detection of precancerous lesions, and it is evident that every woman above the age of 25–30 years must be recommended for cervical screening. Wolters Kluwer - Medknow 2022-09 2022-10-14 /pmc/articles/PMC9731055/ /pubmed/36505559 http://dx.doi.org/10.4103/jfmpc.jfmpc_68_22 Text en Copyright: © 2022 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Mishra, Ruchi
Bisht, Dakshina
Gupta, Manisha
Primary screening of cervical cancer by Pap smear in women of reproductive age group
title Primary screening of cervical cancer by Pap smear in women of reproductive age group
title_full Primary screening of cervical cancer by Pap smear in women of reproductive age group
title_fullStr Primary screening of cervical cancer by Pap smear in women of reproductive age group
title_full_unstemmed Primary screening of cervical cancer by Pap smear in women of reproductive age group
title_short Primary screening of cervical cancer by Pap smear in women of reproductive age group
title_sort primary screening of cervical cancer by pap smear in women of reproductive age group
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731055/
https://www.ncbi.nlm.nih.gov/pubmed/36505559
http://dx.doi.org/10.4103/jfmpc.jfmpc_68_22
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