Case report: Severe acute hepatitis in a 22-month-old Chinese boy with Omicron sub-variant BA.2.38

The etiology of severe acute hepatitis (SAH) in children is various. We describe the first Chinese case of severe acute hepatitis in a 22-month-old boy with the mild illness of Omicron sub-variant BA.2.38. With the application of Compound Glycyrrhizin Injection (CGI), the patient gradually recovered...

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Autores principales: Chen, Xinying, Hong, Junbin, Li, Yuxia, An, Caixia, Guo, Jianwen, Yang, Jinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731137/
https://www.ncbi.nlm.nih.gov/pubmed/36504992
http://dx.doi.org/10.3389/fpubh.2022.1012638
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author Chen, Xinying
Hong, Junbin
Li, Yuxia
An, Caixia
Guo, Jianwen
Yang, Jinghua
author_facet Chen, Xinying
Hong, Junbin
Li, Yuxia
An, Caixia
Guo, Jianwen
Yang, Jinghua
author_sort Chen, Xinying
collection PubMed
description The etiology of severe acute hepatitis (SAH) in children is various. We describe the first Chinese case of severe acute hepatitis in a 22-month-old boy with the mild illness of Omicron sub-variant BA.2.38. With the application of Compound Glycyrrhizin Injection (CGI), the patient gradually recovered from acute liver injury (ALI). This case highlights the possibility of severe ALI in children with the non-critical illness of SARS-CoV-2. The management of SAH associated with the pandemic presents challenges for clinicians, and follow-up is in need. The method of differential diagnosis using limited laboratory results is of great value to the clinicians.
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spelling pubmed-97311372022-12-09 Case report: Severe acute hepatitis in a 22-month-old Chinese boy with Omicron sub-variant BA.2.38 Chen, Xinying Hong, Junbin Li, Yuxia An, Caixia Guo, Jianwen Yang, Jinghua Front Public Health Public Health The etiology of severe acute hepatitis (SAH) in children is various. We describe the first Chinese case of severe acute hepatitis in a 22-month-old boy with the mild illness of Omicron sub-variant BA.2.38. With the application of Compound Glycyrrhizin Injection (CGI), the patient gradually recovered from acute liver injury (ALI). This case highlights the possibility of severe ALI in children with the non-critical illness of SARS-CoV-2. The management of SAH associated with the pandemic presents challenges for clinicians, and follow-up is in need. The method of differential diagnosis using limited laboratory results is of great value to the clinicians. Frontiers Media S.A. 2022-11-24 /pmc/articles/PMC9731137/ /pubmed/36504992 http://dx.doi.org/10.3389/fpubh.2022.1012638 Text en Copyright © 2022 Chen, Hong, Li, An, Guo and Yang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Chen, Xinying
Hong, Junbin
Li, Yuxia
An, Caixia
Guo, Jianwen
Yang, Jinghua
Case report: Severe acute hepatitis in a 22-month-old Chinese boy with Omicron sub-variant BA.2.38
title Case report: Severe acute hepatitis in a 22-month-old Chinese boy with Omicron sub-variant BA.2.38
title_full Case report: Severe acute hepatitis in a 22-month-old Chinese boy with Omicron sub-variant BA.2.38
title_fullStr Case report: Severe acute hepatitis in a 22-month-old Chinese boy with Omicron sub-variant BA.2.38
title_full_unstemmed Case report: Severe acute hepatitis in a 22-month-old Chinese boy with Omicron sub-variant BA.2.38
title_short Case report: Severe acute hepatitis in a 22-month-old Chinese boy with Omicron sub-variant BA.2.38
title_sort case report: severe acute hepatitis in a 22-month-old chinese boy with omicron sub-variant ba.2.38
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731137/
https://www.ncbi.nlm.nih.gov/pubmed/36504992
http://dx.doi.org/10.3389/fpubh.2022.1012638
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