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Rapamycin improves the developmental competence of human oocytes by alleviating DNA damage during IVM

STUDY QUESTION: Can rapamycin improve the developmental competence of human oocytes during the IVM process? SUMMARY ANSWER: Rapamycin at 10 nM could markedly improve the developmental competence of human oocytes undergoing IVM. WHAT IS KNOWN ALREADY: Embryos derived from oocytes that mature in vitro...

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Detalles Bibliográficos
Autores principales: Yang, Qiyu, Xi, Qingsong, Wang, Meng, Liu, Jing, Li, Zhou, Hu, Juan, Jin, Lei, Zhu, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731209/
https://www.ncbi.nlm.nih.gov/pubmed/36518986
http://dx.doi.org/10.1093/hropen/hoac050