Cargando…

Nigral volumetric and microstructural measures in individuals with scans without evidence of dopaminergic deficit

INTRODUCTION: Striatal dopamine transporter (DAT) imaging using (123)I-ioflupane single photon positron emitted computed tomography (SPECT) (DaTScan, GE) identifies 5−20% of newly diagnosed Parkinson’s disease (PD) subjects enrolling in clinical studies to have scans without evidence of dopaminergic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Langley, Jason, Hwang, Kristy S., Hu, Xiaoping P., Huddleston, Daniel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731284/ https://www.ncbi.nlm.nih.gov/pubmed/36507343 http://dx.doi.org/10.3389/fnins.2022.1048945

Ejemplares similares

Nigral volume loss in prodromal, early, and moderate Parkinson’s disease
por: Langley, Jason, et al.
Publicado: (2023)

Frontotemporal Lobe Degeneration as Origin of Scans Without Evidence of Dopaminergic Deficit
por: Menéndez-González, Manuel, et al.
Publicado: (2018)

Nigral diffusivity, but not free water, correlates with iron content in Parkinson’s disease
por: Langley, Jason, et al.
Publicado: (2021)

Heptachlor induced nigral dopaminergic neuronal loss and Parkinsonism-like movement deficits in mice
por: Hong, Seokheon, et al.
Publicado: (2014)

Glutamatergic synaptic currents of nigral dopaminergic neurons follow a postnatal developmental sequence
por: Pearlstein, Edouard, et al.
Publicado: (2015)

Discovery of nigral dopaminergic neurogenesis in adult mice
por: Morrison, Brad E.
Publicado: (2016)

Inhibition of Nigral Microglial Activation Reduces Age-Related Loss of Dopaminergic Neurons and Motor Deficits
por: Wang, Tzu-Feng, et al.
Publicado: (2022)

Cerebrospinal fluid biomarkers profile in scans without evidence of dopaminergic deficits (SWEDD)
por: Nabizadeh, Fardin, et al.
Publicado: (2023)

Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease
por: García-Domínguez, Irene, et al.
Publicado: (2018)

Value of Clinical Signs in Identifying Patients with Scans without Evidence of Dopaminergic Deficit (SWEDD)
por: Suwijn, Sven R., et al.
Publicado: (2020)

Dopaminergic Presynaptic Modulation of Nigral Afferents: Its Role in the Generation of Recurrent Bursting in Substantia Nigra Pars Reticulata Neurons
por: de Jesús Aceves, José, et al.
Publicado: (2011)

Epothilone B Benefits Nigral Dopaminergic Neurons by Attenuating Microglia Activation in the 6-Hydroxydopamine Lesion Mouse Model of Parkinson’s Disease
por: Yu, Zhongyuan, et al.
Publicado: (2018)

Application of the Physical Disector Principle for Quantification of Dopaminergic Neuronal Loss in a Rat 6-Hydroxydopamine Nigral Lesion Model of Parkinson's Disease
por: Fabricius, Katrine, et al.
Publicado: (2017)

Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
por: Benner, Eric J., et al.
Publicado: (2008)

Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons
por: Garrido, Manuel, et al.
Publicado: (2010)

Application of flavonoids for the protection of nigral dopaminergic neurons from oxidative stress
por: Kim, Sang Ryong
Publicado: (2020)

Pathophysiological Features of Nigral Dopaminergic Neurons in Animal Models of Parkinson’s Disease
por: Guatteo, Ezia, et al.
Publicado: (2022)

Is Transcranial Sonography Useful to Distinguish Scans Without Evidence of Dopaminergic Deficit Patients From Parkinson's Disease?
por: Stockner, Heike, et al.
Publicado: (2012)

Association of autonomic symptoms with cerebrospinal fluid biomarkers in Parkinson disease and scans without evidence of dopaminergic deficit
por: Yu, Zhenwei, et al.
Publicado: (2021)

Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synuclein
por: Bentea, Eduard, et al.
Publicado: (2015)

Effects of Subthalamic and Nigral Stimulation on Gait Kinematics in Parkinson’s Disease
por: Scholten, Marlieke, et al.
Publicado: (2017)

Patients with scans without evidence of dopaminergic deficit (SWEDD) do not have early Parkinson’s disease: Analysis of the PPMI data
por: Lee, Jeong Won, et al.
Publicado: (2021)

Comparison of resting tremor at the upper limb joints between patients with Parkinson’s disease and scans without evidence of dopaminergic deficit
por: Kwon, Do-Young, et al.
Publicado: (2023)

Down-regulation of microglial activity attenuates axotomized nigral dopaminergic neuronal cell loss
por: Song, Dae-Yong, et al.
Publicado: (2013)

Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo
por: Leem, Eunju, et al.
Publicado: (2018)

Sniffing out cognitive decline in patients with and without evidence of dopaminergic deficit
por: Lopez, Francesca V., et al.
Publicado: (2019)

Nigral Iron Deposition Is Associated With Levodopa-Induced Dyskinesia in Parkinson’s Disease
por: Song, Tianbin, et al.
Publicado: (2021)

In vivo detection of substantia nigra and locus coeruleus volume loss in Parkinson’s disease using neuromelanin-sensitive MRI: Replication in two cohorts
por: Hwang, Kristy S., et al.
Publicado: (2023)

Structural connectivity profile of scans without evidence of dopaminergic deficit (SWEDD) patients compared to normal controls and Parkinson’s disease patients
por: Kim, Mansu, et al.
Publicado: (2016)

Similarities and differences between nigral and enteric dopaminergic neurons unravel distinctive involvement in Parkinson’s disease
por: Chalazonitis, Alcmène, et al.
Publicado: (2022)

Reward expectation enhances action-related activity of nigral dopaminergic and two striatal output pathways
por: Rios, Alain, et al.
Publicado: (2023)

Subcellular Patch-clamp Recordings from the Somatodendritic Domain of Nigral Dopamine Neurons
por: Engel, Dominique
Publicado: (2016)

Dopaminergic foundations of personality and individual differences
por: Smillie, Luke D., et al.
Publicado: (2014)

Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation
por: de Pablos, Rocío M, et al.
Publicado: (2014)

The Neuroprotective Mechanism of Low-Frequency rTMS on Nigral Dopaminergic Neurons of Parkinson's Disease Model Mice
por: Dong, Qiaoyun, et al.
Publicado: (2015)

Nigral dopaminergic neuron replenishment in adult mice through VE-cadherin-expressing neural progenitor cells
por: Rahman, Abir A., et al.
Publicado: (2017)

Ibogaine Administration Modifies GDNF and BDNF Expression in Brain Regions Involved in Mesocorticolimbic and Nigral Dopaminergic Circuits
por: Marton, Soledad, et al.
Publicado: (2019)

Methanolic Extract of Boswellia serrata Gum Protects the Nigral Dopaminergic Neurons from Rotenone-Induced Neurotoxicity
por: Shadfar, Sina, et al.
Publicado: (2022)

Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction
por: Liu, Zhenhua, et al.
Publicado: (2022)

Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity
por: Benskey, Matthew J., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_caevotc245b0lho7dcqqb41drf