Cargando…

Adherence to anti-asthma medications among adult asthmatic patients in Eastern Ethiopia: A multi-center cross-sectional study

INTRODUCTION: Adherence to anti-asthmatic medications plays a vital role in enhancing an asthma patient’s quality of life and prognosis. However, in Ethiopia, the level of adherence and contributing factors were rarely studied. Therefore, this study was conducted to determine the level of adherence...

Descripción completa

Detalles Bibliográficos
Autores principales: Heluf, Helina, Assefa, Nega, Dessie, Yadeta, Tamiru, Dawit, Goshu, Abel Tibebu, Fekadu, Gelana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731407/
https://www.ncbi.nlm.nih.gov/pubmed/36480508
http://dx.doi.org/10.1371/journal.pone.0277796
_version_ 1784845893630951424
author Heluf, Helina
Assefa, Nega
Dessie, Yadeta
Tamiru, Dawit
Goshu, Abel Tibebu
Fekadu, Gelana
author_facet Heluf, Helina
Assefa, Nega
Dessie, Yadeta
Tamiru, Dawit
Goshu, Abel Tibebu
Fekadu, Gelana
author_sort Heluf, Helina
collection PubMed
description INTRODUCTION: Adherence to anti-asthmatic medications plays a vital role in enhancing an asthma patient’s quality of life and prognosis. However, in Ethiopia, the level of adherence and contributing factors were rarely studied. Therefore, this study was conducted to determine the level of adherence to anti-asthma medications and associated factors among adult asthmatic patients in Eastern Ethiopia. METHOD: Institutional based cross-sectional study was conducted at six governmental hospitals found in Eastern Ethiopia. A total of 320 asthma patients aged 18 years and above and using asthma medicines for at least 12 months were involved. An interviewer based structured questionnaires were used to collect the data. Bivariable and multivariable logistic regression analyses were carried out using IBM SPSS version 22 (SPSS, Chicago, IL). The Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI) was used to determine the strength of association between independent variables and outcome variable. Variables with a p-value of ≤ 0.05 were considered statistically significant. RESULT: Of the 320 asthma patients that participated in the study, 109(34.1%:28.8–39.1%) of them had good adherence to anti-asthmatic medications. Being a housewife (AOR = 4.265, 95%CI: 1.333, 13.653), having good knowledge about asthma (AOR = 2.921, 95%CI (1.472, 5.795), positive attitude towards asthma (AOR = 3.129, 95%CI: 1.555, 6.293), and use of oral corticosteroid drugs (AOR = 1.967, 95%CI: 1.008, 3.841) were factors positively associated with good adherence to anti-asthmatic medications. Participants on treatment for 2–3 years (AOR = .295, 95%CI: 0.099, 0.873), and those on medication for ≥ 4 years (AOR = 0.229, 95%CI: 0.079, 0.664) were 70.5% and 77.1% times less likely to adhere to anti-asthmatic medications respectively. CONCLUSION: The current study signified a low level of adherence to anti-asthmatic medications. Participant’s characteristics and medication related factors were significantly associated with good adherence to anti-asthmatic medications. Health education and advice during follow-up for asthma patients is crucial for better adherence.
format Online
Article
Text
id pubmed-9731407
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-97314072022-12-09 Adherence to anti-asthma medications among adult asthmatic patients in Eastern Ethiopia: A multi-center cross-sectional study Heluf, Helina Assefa, Nega Dessie, Yadeta Tamiru, Dawit Goshu, Abel Tibebu Fekadu, Gelana PLoS One Research Article INTRODUCTION: Adherence to anti-asthmatic medications plays a vital role in enhancing an asthma patient’s quality of life and prognosis. However, in Ethiopia, the level of adherence and contributing factors were rarely studied. Therefore, this study was conducted to determine the level of adherence to anti-asthma medications and associated factors among adult asthmatic patients in Eastern Ethiopia. METHOD: Institutional based cross-sectional study was conducted at six governmental hospitals found in Eastern Ethiopia. A total of 320 asthma patients aged 18 years and above and using asthma medicines for at least 12 months were involved. An interviewer based structured questionnaires were used to collect the data. Bivariable and multivariable logistic regression analyses were carried out using IBM SPSS version 22 (SPSS, Chicago, IL). The Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI) was used to determine the strength of association between independent variables and outcome variable. Variables with a p-value of ≤ 0.05 were considered statistically significant. RESULT: Of the 320 asthma patients that participated in the study, 109(34.1%:28.8–39.1%) of them had good adherence to anti-asthmatic medications. Being a housewife (AOR = 4.265, 95%CI: 1.333, 13.653), having good knowledge about asthma (AOR = 2.921, 95%CI (1.472, 5.795), positive attitude towards asthma (AOR = 3.129, 95%CI: 1.555, 6.293), and use of oral corticosteroid drugs (AOR = 1.967, 95%CI: 1.008, 3.841) were factors positively associated with good adherence to anti-asthmatic medications. Participants on treatment for 2–3 years (AOR = .295, 95%CI: 0.099, 0.873), and those on medication for ≥ 4 years (AOR = 0.229, 95%CI: 0.079, 0.664) were 70.5% and 77.1% times less likely to adhere to anti-asthmatic medications respectively. CONCLUSION: The current study signified a low level of adherence to anti-asthmatic medications. Participant’s characteristics and medication related factors were significantly associated with good adherence to anti-asthmatic medications. Health education and advice during follow-up for asthma patients is crucial for better adherence. Public Library of Science 2022-12-08 /pmc/articles/PMC9731407/ /pubmed/36480508 http://dx.doi.org/10.1371/journal.pone.0277796 Text en © 2022 Heluf et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Heluf, Helina
Assefa, Nega
Dessie, Yadeta
Tamiru, Dawit
Goshu, Abel Tibebu
Fekadu, Gelana
Adherence to anti-asthma medications among adult asthmatic patients in Eastern Ethiopia: A multi-center cross-sectional study
title Adherence to anti-asthma medications among adult asthmatic patients in Eastern Ethiopia: A multi-center cross-sectional study
title_full Adherence to anti-asthma medications among adult asthmatic patients in Eastern Ethiopia: A multi-center cross-sectional study
title_fullStr Adherence to anti-asthma medications among adult asthmatic patients in Eastern Ethiopia: A multi-center cross-sectional study
title_full_unstemmed Adherence to anti-asthma medications among adult asthmatic patients in Eastern Ethiopia: A multi-center cross-sectional study
title_short Adherence to anti-asthma medications among adult asthmatic patients in Eastern Ethiopia: A multi-center cross-sectional study
title_sort adherence to anti-asthma medications among adult asthmatic patients in eastern ethiopia: a multi-center cross-sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731407/
https://www.ncbi.nlm.nih.gov/pubmed/36480508
http://dx.doi.org/10.1371/journal.pone.0277796
work_keys_str_mv AT helufhelina adherencetoantiasthmamedicationsamongadultasthmaticpatientsineasternethiopiaamulticentercrosssectionalstudy
AT assefanega adherencetoantiasthmamedicationsamongadultasthmaticpatientsineasternethiopiaamulticentercrosssectionalstudy
AT dessieyadeta adherencetoantiasthmamedicationsamongadultasthmaticpatientsineasternethiopiaamulticentercrosssectionalstudy
AT tamirudawit adherencetoantiasthmamedicationsamongadultasthmaticpatientsineasternethiopiaamulticentercrosssectionalstudy
AT goshuabeltibebu adherencetoantiasthmamedicationsamongadultasthmaticpatientsineasternethiopiaamulticentercrosssectionalstudy
AT fekadugelana adherencetoantiasthmamedicationsamongadultasthmaticpatientsineasternethiopiaamulticentercrosssectionalstudy