mRNA 5′ terminal sequences drive 200-fold differences in expression through effects on synthesis, translation and decay

mRNA regulatory sequences control gene expression at multiple levels including translation initiation and mRNA decay. The 5′ terminal sequences of mRNAs have unique regulatory potential because of their proximity to key post-transcriptional regulators. Here we have systematically probed the function...

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Detalles Bibliográficos
Autores principales: van den Elzen, Antonia M. G., Watson, Maegan J., Thoreen, Carson C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731452/
https://www.ncbi.nlm.nih.gov/pubmed/36441824
http://dx.doi.org/10.1371/journal.pgen.1010532

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