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Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery
Drug discovery for psychiatric conditions is stagnating. Behavioral changes could be used as a primary phenotypic screen for new drug candidates, if enough useful data can be generated from behavioral models. Could machine learning be the answer to extracting the data we need?
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731455/ https://www.ncbi.nlm.nih.gov/pubmed/36480527 http://dx.doi.org/10.1371/journal.pbio.3001904 |
| _version_ | 1784845906143608832 |
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| author | Sweis, Brian M. Nestler, Eric J. |
| author_facet | Sweis, Brian M. Nestler, Eric J. |
| author_sort | Sweis, Brian M. |
| collection | PubMed |
| description | Drug discovery for psychiatric conditions is stagnating. Behavioral changes could be used as a primary phenotypic screen for new drug candidates, if enough useful data can be generated from behavioral models. Could machine learning be the answer to extracting the data we need? |
| format | Online Article Text |
| id | pubmed-9731455 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Public Library of Science |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-97314552022-12-09 Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery Sweis, Brian M. Nestler, Eric J. PLoS Biol Perspective Drug discovery for psychiatric conditions is stagnating. Behavioral changes could be used as a primary phenotypic screen for new drug candidates, if enough useful data can be generated from behavioral models. Could machine learning be the answer to extracting the data we need? Public Library of Science 2022-12-08 /pmc/articles/PMC9731455/ /pubmed/36480527 http://dx.doi.org/10.1371/journal.pbio.3001904 Text en © 2022 Sweis, Nestler https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| spellingShingle | Perspective Sweis, Brian M. Nestler, Eric J. Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery |
| title | Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery |
| title_full | Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery |
| title_fullStr | Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery |
| title_full_unstemmed | Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery |
| title_short | Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery |
| title_sort | pushing the boundaries of behavioral analysis could aid psychiatric drug discovery |
| topic | Perspective |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731455/ https://www.ncbi.nlm.nih.gov/pubmed/36480527 http://dx.doi.org/10.1371/journal.pbio.3001904 |
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