Human Islet Amyloid Polypeptide (hIAPP) Protofibril‐Specific Antibodies for Detection and Treatment of Type 2 Diabetes (Adv. Sci. 34/2022)

Type 2 Diabetes In article number 2202342, Ronald J. Parchem and co‐workers describe two hIAPP protofibril‐specific antibodies which prevent β cell toxicity in type 2 diabetes (T2D). Treatment with mAbs increases survival in a mouse model of severe T2D, and pancreatic islets from treated mice show d...

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Detalles Bibliográficos
Autores principales: Bortoletto, Angelina S., Graham, W. Vallen, Trout, Gabriella, Bonito‐Oliva, Alessandra, Kazmi, Manija A., Gong, Jing, Weyburne, Emily, Houser, Brandy L., Sakmar, Thomas P., Parchem, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731679/
http://dx.doi.org/10.1002/advs.202270217

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