Blockade of Nuclear β‐Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis

Colorectal cancer (CRC) is one of the most common malignant tumors in the world, with high prevalence and low 5‐year survival. Most of the CRC patients show excessive activation of the Wnt/β‐catenin pathway which is a vital target for CRC treatment. Based on multiple CRC cell lines with different nu...

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Detalles Bibliográficos
Autores principales: Zheng, Can‐Can, Liao, Long, Liu, Ya‐Ping, Yang, Yan‐Ming, He, Yan, Zhang, Guo‐Geng, Li, Shu‐Jun, Liu, Ting, Xu, Wen Wen, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731691/
https://www.ncbi.nlm.nih.gov/pubmed/36270974
http://dx.doi.org/10.1002/advs.202202528

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