Host-directed therapy with 2-deoxy-D-glucose inhibits human rhinoviruses, endemic coronaviruses, and SARS-CoV-2

Rhinoviruses (RVs) and coronaviruses (CoVs) upregulate host cell metabolic pathways such as glycolysis to meet their bioenergetic demands for rapid multiplication. Using the glycolysis inhibitor 2-deoxy-d-glucose (2-DG), we assessed the dose-dependent inhibition of viral replication of minor- and ma...

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Detalles Bibliográficos
Autores principales: Wali, Laxmikant, Karbiener, Michael, Chou, Scharon, Kovtunyk, Vitalii, Adonyi, Adam, Gösler, Irene, Contreras, Ximena, Stoeva, Delyana, Blaas, Dieter, Stöckl, Johannes, Kreil, Thomas R., Gualdoni, Guido A., Gorki, Anna-Dorothea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731833/
https://www.ncbi.nlm.nih.gov/pubmed/36514716
http://dx.doi.org/10.1016/j.jve.2022.100305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731833/
https://www.ncbi.nlm.nih.gov/pubmed/36514716
http://dx.doi.org/10.1016/j.jve.2022.100305

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