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T3 and glucose increase expression of phosphoenolpyruvate carboxykinase (PCK1) leading to increased β-cell proliferation

OBJECTIVES: Thyroid hormone (T3) and high glucose concentrations are critical components of β-cell maturation and function. In the present study, we asked whether T3 and glucose signaling pathways coordinately regulate transcription of genes important for β-cell function and proliferation. METHODS:...

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Detalles Bibliográficos
Autores principales:	Katz, Liora S., Argmann, Carmen, Lambertini, Luca, Scott, Donald K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731891/ https://www.ncbi.nlm.nih.gov/pubmed/36455788 http://dx.doi.org/10.1016/j.molmet.2022.101646

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