Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases

Antimicrobial resistance (AMR) is a global health problem. Despite the enormous efforts made in the last decade, threats from some species, including drug-resistant Neisseria gonorrhoeae, continue to rise and would become untreatable. The development of antibiotics with a different mechanism of acti...

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Detalles Bibliográficos
Autores principales: Nishida, Yuya, Yanagisawa, Sachiko, Morita, Rikuri, Shigematsu, Hideki, Shinzawa-Itoh, Kyoko, Yuki, Hitomi, Ogasawara, Satoshi, Shimuta, Ken, Iwamoto, Takashi, Nakabayashi, Chisa, Matsumura, Waka, Kato, Hisakazu, Gopalasingam, Chai, Nagao, Takemasa, Qaqorh, Tasneem, Takahashi, Yusuke, Yamazaki, Satoru, Kamiya, Katsumasa, Harada, Ryuhei, Mizuno, Nobuhiro, Takahashi, Hideyuki, Akeda, Yukihiro, Ohnishi, Makoto, Ishii, Yoshikazu, Kumasaka, Takashi, Murata, Takeshi, Muramoto, Kazumasa, Tosha, Takehiko, Shiro, Yoshitsugu, Honma, Teruki, Shigeta, Yasuteru, Kubo, Minoru, Takashima, Seiji, Shintani, Yasunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731990/
https://www.ncbi.nlm.nih.gov/pubmed/36481732
http://dx.doi.org/10.1038/s41467-022-34771-y

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