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Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions

Early-life stress (ELS) leads to increased vulnerability to psychiatric disorders including depression later in life. Neuroinflammatory processes have been implicated in ELS-induced negative health outcomes, but how ELS impacts microglia, the main tissue-resident macrophages of the central nervous s...

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Autores principales:	Reemst, Kitty, Kracht, Laura, Kotah, Janssen M., Rahimian, Reza, van Irsen, Astrid A. S., Congrains Sotomayor, Gonzalo, Verboon, Laura N., Brouwer, Nieske, Simard, Sophie, Turecki, Gustavo, Mechawar, Naguib, Kooistra, Susanne M., Eggen, Bart J. L., Korosi, Aniko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731997/ https://www.ncbi.nlm.nih.gov/pubmed/36481769 http://dx.doi.org/10.1038/s41398-022-02265-6

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