Recent miRNA Research in Asthma

PURPOSE OF REVIEW: The study of microRNA in asthma has revealed a vibrant new level of gene regulation underlying asthma pathology. Several miRNAs have been shown to be important in asthma, influencing various biological mechanisms which lead to asthma pathology and symptoms. In addition, miRNAs hav...

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Autores principales: Sharma, Rinku, Tiwari, Anshul, McGeachie, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Asthma (V Ortega, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732064/
https://www.ncbi.nlm.nih.gov/pubmed/36459329
http://dx.doi.org/10.1007/s11882-022-01050-1
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author Sharma, Rinku
Tiwari, Anshul
McGeachie, Michael J.
author_facet Sharma, Rinku
Tiwari, Anshul
McGeachie, Michael J.
author_sort Sharma, Rinku
collection PubMed
description PURPOSE OF REVIEW: The study of microRNA in asthma has revealed a vibrant new level of gene regulation underlying asthma pathology. Several miRNAs have been shown to be important in asthma, influencing various biological mechanisms which lead to asthma pathology and symptoms. In addition, miRNAs have been proposed as biomarkers of asthma affection status, asthma severity, and asthma treatment response. We review all recent asthma-miRNA work, while also presenting comprehensive tables of all miRNA results related to asthma. RECENT FINDINGS: We here reviewed 63 recent studies published reporting asthma and miRNA research, and an additional 14 reviews of the same. We summarized the information for both adult and childhood asthma, as well as research on miRNAs in asthma–COPD overlap syndrome (ACOs), and virus-induced asthma exacerbations. SUMMARY: We attempted to present a comprehensive collection of recently published asthma-associated miRNAs as well as tables of all published asthma-related miRNA results.
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spelling pubmed-97320642022-12-10 Recent miRNA Research in Asthma Sharma, Rinku Tiwari, Anshul McGeachie, Michael J. Curr Allergy Asthma Rep Asthma (V Ortega, Section Editor) PURPOSE OF REVIEW: The study of microRNA in asthma has revealed a vibrant new level of gene regulation underlying asthma pathology. Several miRNAs have been shown to be important in asthma, influencing various biological mechanisms which lead to asthma pathology and symptoms. In addition, miRNAs have been proposed as biomarkers of asthma affection status, asthma severity, and asthma treatment response. We review all recent asthma-miRNA work, while also presenting comprehensive tables of all miRNA results related to asthma. RECENT FINDINGS: We here reviewed 63 recent studies published reporting asthma and miRNA research, and an additional 14 reviews of the same. We summarized the information for both adult and childhood asthma, as well as research on miRNAs in asthma–COPD overlap syndrome (ACOs), and virus-induced asthma exacerbations. SUMMARY: We attempted to present a comprehensive collection of recently published asthma-associated miRNAs as well as tables of all published asthma-related miRNA results. Springer US 2022-12-02 2022 /pmc/articles/PMC9732064/ /pubmed/36459329 http://dx.doi.org/10.1007/s11882-022-01050-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Asthma (V Ortega, Section Editor)
Sharma, Rinku
Tiwari, Anshul
McGeachie, Michael J.
Recent miRNA Research in Asthma
title Recent miRNA Research in Asthma
title_full Recent miRNA Research in Asthma
title_fullStr Recent miRNA Research in Asthma
title_full_unstemmed Recent miRNA Research in Asthma
title_short Recent miRNA Research in Asthma
title_sort recent mirna research in asthma
topic Asthma (V Ortega, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732064/
https://www.ncbi.nlm.nih.gov/pubmed/36459329
http://dx.doi.org/10.1007/s11882-022-01050-1
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