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GSK3 inhibitor suppresses cell growth and metabolic process in FLT3-ITD leukemia cells

Glycogen Synthase Kinase-3 (GSK-3) was recently implicated in the dysregulated biology of acute myeloid leukemia (AML). Low concentrations of GSK-3 inhibitors, SB216763 and BIO, suppressed the proliferation of AML cells with FLT3-ITD as early as 24 h after treatment. BIO was used in subsequent assay...

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Detalles Bibliográficos
Autores principales:	Xia, Jing, Feng, Shuxian, Zhou, Jian, Zhang, Lin, Shi, Dingfang, Wang, Mengjie, Zhu, Yi, Bu, Chaozhi, Xu, Daming, Li, Tianyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732066/ https://www.ncbi.nlm.nih.gov/pubmed/36481875 http://dx.doi.org/10.1007/s12032-022-01899-2

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