Inherited rare variants in homologous recombination and neurodevelopmental genes are associated with increased risk of neuroblastoma

BACKGROUND: Neuroblastoma (NB) is the most common solid extracranial paediatric tumour. Genome-wide association studies have driven the discovery of common risk variants, but no large study has investigated the contribution of rare variants to NB susceptibility. Here, we conducted a whole-exome sequ...

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Detalles Bibliográficos
Autores principales: Bonfiglio, Ferdinando, Lasorsa, Vito Alessandro, Cantalupo, Sueva, D'Alterio, Giuseppe, Aievola, Vincenzo, Boccia, Angelo, Ardito, Martina, Furini, Simone, Renieri, Alessandra, Morini, Martina, Stainczyk, Sabine, Westermann, Frank, Paolella, Giovanni, Eva, Alessandra, Iolascon, Achille, Capasso, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732128/
https://www.ncbi.nlm.nih.gov/pubmed/36493725
http://dx.doi.org/10.1016/j.ebiom.2022.104395

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