Cargando…
Experimental and probabilistic model validation of ultrasonic MEMS transceiver for blood glucose sensing
In contrast to traditional laboratory glucose monitoring, recent developments have focused on blood glucose self-monitoring and providing patients with a self-monitoring device. This paper proposes a system based on ultrasound principles for quantifying glucose levels in blood by conducting an in-vi...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732296/ https://www.ncbi.nlm.nih.gov/pubmed/36481774 http://dx.doi.org/10.1038/s41598-022-25717-x |
_version_ | 1784846097835884544 |
---|---|
author | Tripathy, Hara Prasada Pattanaik, Priyabrata Mishra, Dilip Kumar Kamilla, Sushanta Kumar Holderbaum, William |
author_facet | Tripathy, Hara Prasada Pattanaik, Priyabrata Mishra, Dilip Kumar Kamilla, Sushanta Kumar Holderbaum, William |
author_sort | Tripathy, Hara Prasada |
collection | PubMed |
description | In contrast to traditional laboratory glucose monitoring, recent developments have focused on blood glucose self-monitoring and providing patients with a self-monitoring device. This paper proposes a system based on ultrasound principles for quantifying glucose levels in blood by conducting an in-vitro experiment with goat blood before human blood. The ultrasonic transceiver is powered by a frequency generator that operates at 40 kHz and 1.6 V, and variations in glucose level affect the ultrasonic transceiver readings. The RVM probabilistic model is used to determine the variation in glucose levels in a blood sample. Blood glucose levels are measured simultaneously using a commercial glucose metre for confirmation. The experimental data values proposed are highly correlated with commercial glucose metre readings. The proposed ultrasonic MEMS-based blood glucometer measures a glucose level of [Formula: see text] mg/dl. In the near future, the miniature version of the experimental model may be useful to human society. |
format | Online Article Text |
id | pubmed-9732296 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-97322962022-12-10 Experimental and probabilistic model validation of ultrasonic MEMS transceiver for blood glucose sensing Tripathy, Hara Prasada Pattanaik, Priyabrata Mishra, Dilip Kumar Kamilla, Sushanta Kumar Holderbaum, William Sci Rep Article In contrast to traditional laboratory glucose monitoring, recent developments have focused on blood glucose self-monitoring and providing patients with a self-monitoring device. This paper proposes a system based on ultrasound principles for quantifying glucose levels in blood by conducting an in-vitro experiment with goat blood before human blood. The ultrasonic transceiver is powered by a frequency generator that operates at 40 kHz and 1.6 V, and variations in glucose level affect the ultrasonic transceiver readings. The RVM probabilistic model is used to determine the variation in glucose levels in a blood sample. Blood glucose levels are measured simultaneously using a commercial glucose metre for confirmation. The experimental data values proposed are highly correlated with commercial glucose metre readings. The proposed ultrasonic MEMS-based blood glucometer measures a glucose level of [Formula: see text] mg/dl. In the near future, the miniature version of the experimental model may be useful to human society. Nature Publishing Group UK 2022-12-08 /pmc/articles/PMC9732296/ /pubmed/36481774 http://dx.doi.org/10.1038/s41598-022-25717-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Tripathy, Hara Prasada Pattanaik, Priyabrata Mishra, Dilip Kumar Kamilla, Sushanta Kumar Holderbaum, William Experimental and probabilistic model validation of ultrasonic MEMS transceiver for blood glucose sensing |
title | Experimental and probabilistic model validation of ultrasonic MEMS transceiver for blood glucose sensing |
title_full | Experimental and probabilistic model validation of ultrasonic MEMS transceiver for blood glucose sensing |
title_fullStr | Experimental and probabilistic model validation of ultrasonic MEMS transceiver for blood glucose sensing |
title_full_unstemmed | Experimental and probabilistic model validation of ultrasonic MEMS transceiver for blood glucose sensing |
title_short | Experimental and probabilistic model validation of ultrasonic MEMS transceiver for blood glucose sensing |
title_sort | experimental and probabilistic model validation of ultrasonic mems transceiver for blood glucose sensing |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732296/ https://www.ncbi.nlm.nih.gov/pubmed/36481774 http://dx.doi.org/10.1038/s41598-022-25717-x |
work_keys_str_mv | AT tripathyharaprasada experimentalandprobabilisticmodelvalidationofultrasonicmemstransceiverforbloodglucosesensing AT pattanaikpriyabrata experimentalandprobabilisticmodelvalidationofultrasonicmemstransceiverforbloodglucosesensing AT mishradilipkumar experimentalandprobabilisticmodelvalidationofultrasonicmemstransceiverforbloodglucosesensing AT kamillasushantakumar experimentalandprobabilisticmodelvalidationofultrasonicmemstransceiverforbloodglucosesensing AT holderbaumwilliam experimentalandprobabilisticmodelvalidationofultrasonicmemstransceiverforbloodglucosesensing |