LncRNA CCAT2, involving miR-34a/TGF-β1/Smad4 signaling, regulate hepatic stellate cells proliferation

miR-34a targeting on Smad4 plays important role in TGF-β1 pathway which is a dominant factor for balancing collagen production and degradation in hepatic stellate cells. TGF-β1/Smad4 regulated collagen deposition is a hallmark of hepatic fibrosis. The potential regulation on miR-34a by LncRNAs in he...

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Detalles Bibliográficos
Autores principales: Gao, Haibing, Wang, Xiangmei, Ma, Huaxi, Lin, Shenglong, Zhang, Dongqing, Wu, Wenjun, Liao, Ziyuan, Chen, Mengyun, Ye, Hanhui, Li, Qin, Lin, Minghua, Li, Dongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732356/
https://www.ncbi.nlm.nih.gov/pubmed/36482069
http://dx.doi.org/10.1038/s41598-022-25738-6

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