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Conserved degronome features governing quality control associated proteolysis
The eukaryotic proteome undergoes constant surveillance by quality control systems that either sequester, refold, or eliminate aberrant proteins by ubiquitin-dependent mechanisms. Ubiquitin-conjugation necessitates the recognition of degradation determinants, termed degrons, by their cognate E3 ubiq...
Autores principales: | Mashahreh, Bayan, Armony, Shir, Johansson, Kristoffer Enøe, Chappleboim, Alon, Friedman, Nir, Gardner, Richard G., Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten, Ravid, Tommer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732359/ https://www.ncbi.nlm.nih.gov/pubmed/36481666 http://dx.doi.org/10.1038/s41467-022-35298-y |
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