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Discovery and structure of a widespread bacterial ABC transporter specific for ergothioneine

L-Ergothioneine (ET), the 2-thioimidazole derivative of trimethylhistidine, is biosynthesized by select fungi and bacteria, notably Mycobacterium tuberculosis, and functions as a scavenger of reactive oxygen species. The extent to which ET broadly functions in bacterial cells unable to synthesize it...

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Detalles Bibliográficos
Autores principales: Zhang, Yifan, Gonzalez-Gutierrez, Giovanni, Legg, Katherine A., Walsh, Brenna J. C., Pis Diez, Cristian M., Edmonds, Katherine A., Giedroc, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732360/
https://www.ncbi.nlm.nih.gov/pubmed/36481738
http://dx.doi.org/10.1038/s41467-022-35277-3