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Oxygen-enriched oleic matrix (NovoX) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: Preliminary experience
INTRODUCTION: Pilonidal disease (PD) is a common infectious and inflammatory condition affecting the gluteal cleft and sacrococcygeal region. The optimal treatment for PD remains controversial. While the open technique reduces the number of relapses compared to minimally invasive approaches, it is a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732366/ https://www.ncbi.nlm.nih.gov/pubmed/36507121 http://dx.doi.org/10.3389/fped.2022.1068280 |
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author | Bisol, Marta Tykhomyrova, Sophia Pagliara, Camilla Scarpa, Maria-Grazia Guida, Edoardo Olenik, Damiana Codrich, Daniela Schleef, Jürgen Boscarelli, Alessandro |
author_facet | Bisol, Marta Tykhomyrova, Sophia Pagliara, Camilla Scarpa, Maria-Grazia Guida, Edoardo Olenik, Damiana Codrich, Daniela Schleef, Jürgen Boscarelli, Alessandro |
author_sort | Bisol, Marta |
collection | PubMed |
description | INTRODUCTION: Pilonidal disease (PD) is a common infectious and inflammatory condition affecting the gluteal cleft and sacrococcygeal region. The optimal treatment for PD remains controversial. While the open technique reduces the number of relapses compared to minimally invasive approaches, it is associated with a longer healing time. Reactive oxygen species are a key part of the normal wound-healing process. Herein, we reported our preliminary experience using a new oxygen-enriched oil-based product called NovoX for wound healing after open surgery for PD. MATERIALS AND METHODS: We used a new oxygen-enriched product for wound healing in three pediatric patients undergoing open surgical repair for PD between December 2021 and April 2022. During postoperative follow-up, healing time and the aesthetic result were evaluated. RESULTS: Our preliminary study included three patients with chronic PD. The average follow-up time was 5 weeks, corresponding to the end of the healing process and the resumption of normal daily activities. Only one mild complication occurred during the study period. No short-term side effects were reported. The cosmetic result was reported as satisfactory. CONCLUSION: NovoX is easy to apply, safe, and effective for treating pediatric patients undergoing open surgical treatment for PD, leading to slightly faster wound healing with good aesthetic outcomes. |
format | Online Article Text |
id | pubmed-9732366 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97323662022-12-10 Oxygen-enriched oleic matrix (NovoX) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: Preliminary experience Bisol, Marta Tykhomyrova, Sophia Pagliara, Camilla Scarpa, Maria-Grazia Guida, Edoardo Olenik, Damiana Codrich, Daniela Schleef, Jürgen Boscarelli, Alessandro Front Pediatr Pediatrics INTRODUCTION: Pilonidal disease (PD) is a common infectious and inflammatory condition affecting the gluteal cleft and sacrococcygeal region. The optimal treatment for PD remains controversial. While the open technique reduces the number of relapses compared to minimally invasive approaches, it is associated with a longer healing time. Reactive oxygen species are a key part of the normal wound-healing process. Herein, we reported our preliminary experience using a new oxygen-enriched oil-based product called NovoX for wound healing after open surgery for PD. MATERIALS AND METHODS: We used a new oxygen-enriched product for wound healing in three pediatric patients undergoing open surgical repair for PD between December 2021 and April 2022. During postoperative follow-up, healing time and the aesthetic result were evaluated. RESULTS: Our preliminary study included three patients with chronic PD. The average follow-up time was 5 weeks, corresponding to the end of the healing process and the resumption of normal daily activities. Only one mild complication occurred during the study period. No short-term side effects were reported. The cosmetic result was reported as satisfactory. CONCLUSION: NovoX is easy to apply, safe, and effective for treating pediatric patients undergoing open surgical treatment for PD, leading to slightly faster wound healing with good aesthetic outcomes. Frontiers Media S.A. 2022-11-25 /pmc/articles/PMC9732366/ /pubmed/36507121 http://dx.doi.org/10.3389/fped.2022.1068280 Text en © 2022 Bisol, Tykhomyrova, Pagliara, Scarpa, Guida, Olenik, Codrich, Schleef and Boscarelli. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Bisol, Marta Tykhomyrova, Sophia Pagliara, Camilla Scarpa, Maria-Grazia Guida, Edoardo Olenik, Damiana Codrich, Daniela Schleef, Jürgen Boscarelli, Alessandro Oxygen-enriched oleic matrix (NovoX) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: Preliminary experience |
title | Oxygen-enriched oleic matrix (NovoX) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: Preliminary experience |
title_full | Oxygen-enriched oleic matrix (NovoX) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: Preliminary experience |
title_fullStr | Oxygen-enriched oleic matrix (NovoX) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: Preliminary experience |
title_full_unstemmed | Oxygen-enriched oleic matrix (NovoX) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: Preliminary experience |
title_short | Oxygen-enriched oleic matrix (NovoX) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: Preliminary experience |
title_sort | oxygen-enriched oleic matrix (novox) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: preliminary experience |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732366/ https://www.ncbi.nlm.nih.gov/pubmed/36507121 http://dx.doi.org/10.3389/fped.2022.1068280 |
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