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Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure
In vitro assembly of amyloid fibrils that recapitulate those in human brains is very useful for fundamental and applied research on the amyloid formation, pathology, and clinical detection. Recent success in the assembly of Tau fibrils in vitro enables the recapitulation of the paired helical filame...
Autores principales: | Li, Xiang, Zhang, Shenqing, Liu, Zhengtao, Tao, Youqi, Xia, Wencheng, Sun, Yunpeng, Liu, Cong, Le, Weidong, Sun, Bo, Li, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732399/ https://www.ncbi.nlm.nih.gov/pubmed/36505939 http://dx.doi.org/10.1016/j.isci.2022.105645 |
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