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Identification of an immunogenic epitope and protective antibody against the furin cleavage site of SARS-CoV-2
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the global coronavirus disease 2019 (COVID-19) pandemic, contains a unique, four amino acid (aa) “PRRA” insertion in the spike (S) protein that creates a transmembrane protease serine 2 (TMPRSS2)/furin c...
Autores principales: | Li, Lili, Gao, Meiling, Li, Jie, Xie, Xuping, Zhao, Hui, Wang, Yanan, Xu, Xin, Zu, Shulong, Chen, Chunfeng, Wan, Dingyi, Duan, Jing, Wang, Jingfeng, Aliyari, Saba R., Gold, Sarah, Zhang, Jicai, Qin, Cheng-Feng, Shi, Pei-Yong, Yang, Heng, Cheng, Genhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732504/ https://www.ncbi.nlm.nih.gov/pubmed/36508877 http://dx.doi.org/10.1016/j.ebiom.2022.104401 |
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