PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells

IL-17A–producing γδ T cells in mice consist primarily of Vγ6(+) tissue-resident cells and Vγ4(+) circulating cells. How these γδ T cell subsets are regulated during homeostasis and cancer remains poorly understood. Using single-cell RNA sequencing and flow cytommetry, we show that lung Vγ4(+) and Vγ...

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Detalles Bibliográficos
Autores principales: Edwards, Sarah C., Hedley, Ann, Hoevenaar, Wilma H.M., Wiesheu, Robert, Glauner, Teresa, Kilbey, Anna, Shaw, Robin, Boufea, Katerina, Batada, Nizar, Hatano, Shinya, Yoshikai, Yasunobu, Blyth, Karen, Miller, Crispin, Kirschner, Kristina, Coffelt, Seth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732671/
https://www.ncbi.nlm.nih.gov/pubmed/36480166
http://dx.doi.org/10.1084/jem.20211431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732671/
https://www.ncbi.nlm.nih.gov/pubmed/36480166
http://dx.doi.org/10.1084/jem.20211431

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