Platelet caspase‐1 and Bruton tyrosine kinase activation in patients with COVID‐19 is associated with disease severity and reversed in vitro by ibrutinib

BACKGROUND: Severity of coronavirus disease 2019 (COVID‐19) is often associated with thrombotic complications and cytokine storm leading to intensive are unit (ICU) admission. Platelets are known to be responsible for abnormal hemostasis parameters (thrombocytopenia, raised D‐dimers, and prolonged p...

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Detalles Bibliográficos
Autores principales: Claude, Livia, Martino, Frédéric, Hermand, Patricia, Chahim, Bassel, Roger, Pierre‐Marie, de Bourayne, Marie, Garnier, Yohann, Tressieres, Benoit, Colin, Yves, Le Van Kim, Caroline, Romana, Marc, Baccini, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732813/
https://www.ncbi.nlm.nih.gov/pubmed/36514346
http://dx.doi.org/10.1002/rth2.12811

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