Radiochemical Synthesis and Evaluation of 3-[(11)C]Methyl-4-aminopyridine in Rodents and Nonhuman Primates for Imaging Potassium Channels in the CNS

[Image: see text] Demyelination, the loss of the insulating sheath of neurons, causes failed or slowed neuronal conduction and contributes to the neurological symptoms in multiple sclerosis, traumatic brain and spinal cord injuries, stroke, and dementia. In demyelinated neurons, the axonal potassium...

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Detalles Bibliográficos
Autores principales: Sun, Yang, Guehl, Nicolas J., Zhou, Yu-Peng, Takahashi, Kazue, Belov, Vasily, Dhaynaut, Maeva, Moon, Sung-Hyun, El Fakhri, Georges, Normandin, Marc D., Brugarolas, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732819/
https://www.ncbi.nlm.nih.gov/pubmed/36417797
http://dx.doi.org/10.1021/acschemneuro.2c00364

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