Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region

[Image: see text] Brain-derived neurotrophic factor (BDNF) is a neurotrophin (NT) essential for neuronal development and synaptic plasticity. Dysregulation of BDNF signaling is implicated in different neurological disorders. The direct NT administration as therapeutics has revealed to be challenging...

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Detalles Bibliográficos
Autores principales: Russo, Lara, Giacomelli, Chiara, Fortino, Mariagrazia, Marzo, Tiziano, Ferri, Gianmarco, Calvello, Mariantonietta, Viegi, Alessandro, Magrì, Antonio, Pratesi, Alessandro, Pietropaolo, Adriana, Cardarelli, Francesco, Martini, Claudia, Rizzarelli, Enrico, Marchetti, Laura, La Mendola, Diego, Trincavelli, Maria Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732821/
https://www.ncbi.nlm.nih.gov/pubmed/36346920
http://dx.doi.org/10.1021/acschemneuro.2c00463

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