Cargando…

USP7 substrates identified by proteomics analysis reveal the specificity of USP7

Deubiquitylating enzymes (DUBs) remove ubiquitin chains from proteins and regulate protein stability and function. USP7 is one of the most extensively studied DUBs, since USP7 has several well-known substrates important for cancer progression, such as MDM2, N-MYC, and PTEN. Thus, USP7 is a promising...

Descripción completa

Detalles Bibliográficos
Autores principales: Nie, Litong, Wang, Chao, Liu, Xiaoguang, Teng, Hongqi, Li, Siting, Huang, Min, Feng, Xu, Pei, Guangsheng, Hang, Qinglei, Zhao, Zhongming, Gan, Boyi, Ma, Li, Chen, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732911/
https://www.ncbi.nlm.nih.gov/pubmed/36302555
http://dx.doi.org/10.1101/gad.349848.122