Exosomal LINC00460/miR-503-5p/ANLN positive feedback loop aggravates pancreatic cancer progression through regulating T cell–mediated cytotoxicity and PD-1 checkpoint

BACKGROUND: Long non-coding RNA (lncRNA) LINC00460 is an onco-lncRNA in a variety of cancers, including pancreatic cancer (PC). This study is aimed to investigate the regulatory mechanisms of LINC00460 in PC. METHODS: The tumor and adjacent normal tissues were collected from 73 PC patients. The expr...

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Detalles Bibliográficos
Autores principales: Yao, Jun, Gao, Ruoyu, Luo, Minghan, Li, Defeng, Guo, Liliangzi, Yu, Zichao, Xiong, Feng, Wei, Cheng, Wu, Benhua, Xu, Zhenglei, Zhang, Dingguo, Wang, Jianyao, Wang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733079/
https://www.ncbi.nlm.nih.gov/pubmed/36482354
http://dx.doi.org/10.1186/s12935-022-02741-5

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