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Schwannomas of the greater superficial petrosal nerve – case series, discussion of surgical techniques, and review of literature

BACKGROUND: Facial nerve schwannomas account for about 0.8% of all petrous mass lesions. Schwannomas of the greater superficial petrosal nerve (GSPN) are a rare subtype with few case-reports up to date. CASE PRESENTATIONS: A retrospective analysis of clinical outcomes, radiographic findings and post...

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Autores principales: Aftahy, A. Kaywan, Groll, Maximilian, Wagner, Arthur, Barz, Melanie, Bernhardt, Denise, Combs, Stephanie E., Meyer, Bernhard, Gempt, Jens, Negwer, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733176/
https://www.ncbi.nlm.nih.gov/pubmed/36494617
http://dx.doi.org/10.1186/s12883-022-02960-3
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author Aftahy, A. Kaywan
Groll, Maximilian
Wagner, Arthur
Barz, Melanie
Bernhardt, Denise
Combs, Stephanie E.
Meyer, Bernhard
Gempt, Jens
Negwer, Chiara
author_facet Aftahy, A. Kaywan
Groll, Maximilian
Wagner, Arthur
Barz, Melanie
Bernhardt, Denise
Combs, Stephanie E.
Meyer, Bernhard
Gempt, Jens
Negwer, Chiara
author_sort Aftahy, A. Kaywan
collection PubMed
description BACKGROUND: Facial nerve schwannomas account for about 0.8% of all petrous mass lesions. Schwannomas of the greater superficial petrosal nerve (GSPN) are a rare subtype with few case-reports up to date. CASE PRESENTATIONS: A retrospective analysis of clinical outcomes, radiographic findings and postoperative complication between June 2007 and December 2020 was performed. Four cases of GSPN schwannomas were reported. The presenting symptoms were facial nerve palsy and hearing loss. Imaging studies showed a subtemporal mass on the anterosuperior aspect of the petrous bone, in one case with extraordinary petrous bone and mastoid infiltration and destruction. Three cases were removed through a subtemporal extra- or intradural approach, one case via a combined pre- and retrosigmoid approach. Improvement of facial nerve palsy occurred in one case; new hearing loss was observed in another case. Xeropthalmia was a short-term temporary deficit in three cases. Short- to mid-term follow-up of the patients has not shown any tumor recurrence. CONCLUSIONS: GSPN schwannomas are rare entities presenting with heterogenous symptoms. Our surgical findings emphasize safe resection. Complete remission is possible by GTR. Since the small data set limits the expressiveness of statements regarding standard of care and alternative therapy options, additional data is needed.
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spelling pubmed-97331762022-12-10 Schwannomas of the greater superficial petrosal nerve – case series, discussion of surgical techniques, and review of literature Aftahy, A. Kaywan Groll, Maximilian Wagner, Arthur Barz, Melanie Bernhardt, Denise Combs, Stephanie E. Meyer, Bernhard Gempt, Jens Negwer, Chiara BMC Neurol Case Report BACKGROUND: Facial nerve schwannomas account for about 0.8% of all petrous mass lesions. Schwannomas of the greater superficial petrosal nerve (GSPN) are a rare subtype with few case-reports up to date. CASE PRESENTATIONS: A retrospective analysis of clinical outcomes, radiographic findings and postoperative complication between June 2007 and December 2020 was performed. Four cases of GSPN schwannomas were reported. The presenting symptoms were facial nerve palsy and hearing loss. Imaging studies showed a subtemporal mass on the anterosuperior aspect of the petrous bone, in one case with extraordinary petrous bone and mastoid infiltration and destruction. Three cases were removed through a subtemporal extra- or intradural approach, one case via a combined pre- and retrosigmoid approach. Improvement of facial nerve palsy occurred in one case; new hearing loss was observed in another case. Xeropthalmia was a short-term temporary deficit in three cases. Short- to mid-term follow-up of the patients has not shown any tumor recurrence. CONCLUSIONS: GSPN schwannomas are rare entities presenting with heterogenous symptoms. Our surgical findings emphasize safe resection. Complete remission is possible by GTR. Since the small data set limits the expressiveness of statements regarding standard of care and alternative therapy options, additional data is needed. BioMed Central 2022-12-09 /pmc/articles/PMC9733176/ /pubmed/36494617 http://dx.doi.org/10.1186/s12883-022-02960-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Aftahy, A. Kaywan
Groll, Maximilian
Wagner, Arthur
Barz, Melanie
Bernhardt, Denise
Combs, Stephanie E.
Meyer, Bernhard
Gempt, Jens
Negwer, Chiara
Schwannomas of the greater superficial petrosal nerve – case series, discussion of surgical techniques, and review of literature
title Schwannomas of the greater superficial petrosal nerve – case series, discussion of surgical techniques, and review of literature
title_full Schwannomas of the greater superficial petrosal nerve – case series, discussion of surgical techniques, and review of literature
title_fullStr Schwannomas of the greater superficial petrosal nerve – case series, discussion of surgical techniques, and review of literature
title_full_unstemmed Schwannomas of the greater superficial petrosal nerve – case series, discussion of surgical techniques, and review of literature
title_short Schwannomas of the greater superficial petrosal nerve – case series, discussion of surgical techniques, and review of literature
title_sort schwannomas of the greater superficial petrosal nerve – case series, discussion of surgical techniques, and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733176/
https://www.ncbi.nlm.nih.gov/pubmed/36494617
http://dx.doi.org/10.1186/s12883-022-02960-3
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