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TSPAN4-positive migrasome derived from retinal pigmented epithelium cells contributes to the development of proliferative vitreoretinopathy

BACKGROUND: Proliferative vitreoretinopathy (PVR) is a blind-causing disease initiated by the activation of retinal pigmented epithelium (RPE) primarily induced by TGF-β families. Migrasome is a recently discovered type of extracellular vesicle related to cell migration. RESULTS: Here, we used ex vi...

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Detalles Bibliográficos
Autores principales: Wu, Liangjing, Yang, Shuai, Li, Hui, Zhang, Yao, Feng, Le, Zhang, Conghui, Wei, Jiayi, Gu, Xunyi, Xu, Guotong, Wang, Zhaoyang, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733225/
https://www.ncbi.nlm.nih.gov/pubmed/36494806
http://dx.doi.org/10.1186/s12951-022-01732-y