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Functional insights from targeted imaging BACE1: the first near-infrared fluorescent probe for Alzheimer’s disease diagnosis

BACKGROUND: β-Secretase (BACE1) is the vital enzyme in the pathogenic processes of Alzheimer's disease (AD). However, the development of a powerful tool with sensitivity for BACE1 determination in vivo is a challenge. METHODS: A novel NIR fluorescent probe HBAE was synthetized from 2-hydroxy-3-...

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Detalles Bibliográficos
Autores principales:	Bi, Anyao, Wu, Junyong, Huang, Shuai, Li, Yongjiang, Zheng, Fan, Ding, Jipeng, Dong, Jie, Xiang, Daxiong, Zeng, Wenbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733252/ https://www.ncbi.nlm.nih.gov/pubmed/36494704 http://dx.doi.org/10.1186/s40824-022-00320-3

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