Cargando…

Altered frontal connectivity as a mechanism for executive function deficits in fragile X syndrome

BACKGROUND: Fragile X syndrome (FXS) is the leading inherited monogenic cause of intellectual disability and autism spectrum disorder. Executive function (EF), necessary for adaptive goal-oriented behavior and dependent on frontal lobe function, is impaired in individuals with FXS. Yet, little is kn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schmitt, Lauren M., Li, Joy, Liu, Rui, Horn, Paul S., Sweeney, John A., Erickson, Craig A., Pedapati, Ernest V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733336/ https://www.ncbi.nlm.nih.gov/pubmed/36494861 http://dx.doi.org/10.1186/s13229-022-00527-0

Ejemplares similares

A neurophysiological model of speech production deficits in fragile X syndrome
por: Schmitt, Lauren M, et al.
Publicado: (2019)

Empirical Frequency Bound Derivation Reveals Prominent Mid-Frontal Alpha Associated with Neurosensory Dysfunction in Fragile X Syndrome
por: Pedapati, Ernest V, et al.
Publicado: (2023)

A resting EEG study of neocortical hyperexcitability and altered functional connectivity in fragile X syndrome
por: Wang, Jun, et al.
Publicado: (2017)

Neural synchronization deficits linked to cortical hyper-excitability and auditory hypersensitivity in fragile X syndrome
por: Ethridge, Lauren E., et al.
Publicado: (2017)

Erratum to: Neural synchronization deficits linked to cortical hyper-excitability and auditory hypersensitivity in fragile X syndrome
por: Ethridge, Lauren E., et al.
Publicado: (2017)

Peripheral Amyloid Precursor Protein Derivative Expression in Fragile X Syndrome
por: McLane, Richard D., et al.
Publicado: (2019)

Executive Function in Fragile X Syndrome: A Systematic Review
por: Schmitt, Lauren M., et al.
Publicado: (2019)

The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development
por: Shaffer, Rebecca C., et al.
Publicado: (2020)

Auditory EEG Biomarkers in Fragile X Syndrome: Clinical Relevance
por: Ethridge, Lauren E., et al.
Publicado: (2019)

Baclofen-associated neurophysiologic target engagement across species in fragile X syndrome
por: Jonak, Carrie R., et al.
Publicado: (2022)

Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome
por: Pedapati, Ernest V., et al.
Publicado: (2022)

Examination of Correlates to Health-Related Quality of Life in Individuals with Fragile X Syndrome
por: Coffman, Marika C., et al.
Publicado: (2020)

Hypersensitivity to Distractors in Fragile X Syndrome from Loss of Modulation of Cortical VIP Interneurons
por: Rahmatullah, Noorhan, et al.
Publicado: (2023)

Hypersensitivity to distractors in Fragile X syndrome from loss of modulation of cortical VIP interneurons
por: Rahmatullah, Noorhan, et al.
Publicado: (2023)

A Pilot Quantitative Evaluation of Early Life Language Development in Fragile X Syndrome
por: Reisinger, Debra L., et al.
Publicado: (2019)

Differentiating social preference and social anxiety phenotypes in fragile X syndrome using an eye gaze analysis: a pilot study
por: Hong, Michael P., et al.
Publicado: (2019)

Fragile X targeted pharmacotherapy: lessons learned and future directions
por: Erickson, Craig A., et al.
Publicado: (2017)

Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible.
por: Goel, Anubhuti, et al.
Publicado: (2018)

Executive Function and Working Memory Deficits in Females with Fragile X Premutation
por: Segal, Osnat, et al.
Publicado: (2023)

Can We Push the “Quasi-Perfect Artifact Rejection” Even Closer to Perfection?
por: Miyakoshi, Makoto, et al.
Publicado: (2021)

Behavioral inflexibility in fragile X syndrome: Accounts from caregivers and self-advocates
por: Jones, Angelina, et al.
Publicado: (2023)

Motor cortex facilitation: a marker of attention deficit hyperactivity disorder co-occurrence in autism spectrum disorder
por: Pedapati, Ernest V., et al.
Publicado: (2019)

Evidence for Three Subgroups of Female FMR1 Premutation Carriers Defined by Distinct Neuropsychiatric Features: A Pilot Study
por: Schmitt, Lauren M., et al.
Publicado: (2022)

A Paradigm Shifting View of Intellectual Disability: A Near Normal Distribution of IQ in Fragile X Syndrome
por: Schmitt, Lauren M., et al.
Publicado: (2023)

Developmental studies in fragile X syndrome
por: Razak, Khaleel A., et al.
Publicado: (2020)

Parallel learning and cognitive flexibility impairments between Fmr1 knockout mice and individuals with fragile X syndrome
por: Schmitt, Lauren M., et al.
Publicado: (2023)

Executive deficits are related to the inferior frontal junction in early dementia
por: Schroeter, Matthias L., et al.
Publicado: (2012)

A sensitive and reproducible qRT-PCR assay detects physiological relevant trace levels of FMR1 mRNA in individuals with Fragile X syndrome
por: Straub, Devan, et al.
Publicado: (2023)

Neuropsychiatric feature-based subgrouping reveals neural sensory processing spectrum in female FMR1 premutation carriers: A pilot study
por: Norris, Jordan E., et al.
Publicado: (2023)

Frontal interhemispheric structural connectivity, attention, and executive function in children with perinatal stroke
por: Larsen, Nicole, et al.
Publicado: (2021)

Emerging pharmacologic treatment options for fragile X syndrome
por: Schaefer, Tori L, et al.
Publicado: (2015)

Optimization, validation and initial clinical implications of a Luminex-based immunoassay for the quantification of Fragile X Protein from dried blood spots
por: Boggs, Anna E., et al.
Publicado: (2022)

Targeted Therapy of Cognitive Deficits in Fragile X Syndrome
por: Puścian, A., et al.
Publicado: (2022)

Executive functional deficits during electrical stimulation of the right frontal aslant tract
por: Rutten, Geert-Jan M., et al.
Publicado: (2021)

A Patient with Fragile X-Associated Tremor/Ataxia Syndrome Presenting with Executive Cognitive Deficits and Cerebral White Matter Lesions
por: Kasuga, Kensaku, et al.
Publicado: (2011)

Altered structural and causal connectivity in frontal lobe epilepsy
por: Klugah-Brown, Benjamin, et al.
Publicado: (2019)

Descriptive analysis of seizures and comorbidities associated with fragile X syndrome
por: Albizua, Igor, et al.
Publicado: (2022)

Visual motion processing deficits in infants with the fragile X premutation
por: Gallego, Pamela K, et al.
Publicado: (2014)

Primary Ciliary Deficits in the Dentate Gyrus of Fragile X Syndrome
por: Lee, Bumwhee, et al.
Publicado: (2020)

Interneuron Dysfunction and Inhibitory Deficits in Autism and Fragile X Syndrome
por: Nomura, Toshihiro
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_m3kav7vmj9nn6q84g7ks2kb06t