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Identification of CEACAM5 as a stemness-related inhibitory immune checkpoint in pancreatic cancer
BACKGROUND: Immunotherapy has emerged as a new cancer treatment modality. However, tumour heterogeneity can diminish checkpoint blockade response and shorten patient survival. As a source of tumour heterogeneity, cancer stem cells act as an indispensable reservoir for local recurrence and distant me...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733357/ https://www.ncbi.nlm.nih.gov/pubmed/36494785 http://dx.doi.org/10.1186/s12885-022-10397-7 |