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Bridging the genomic data gap in Africa: implications for global disease burdens
This paper highlights the gap in the use of genomic data of Africans for global research efforts for disease cures. Genomic data represents an important tool used in disease research for understanding how diseases affect several populations and how these differences can be harnessed for the developm...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733397/ https://www.ncbi.nlm.nih.gov/pubmed/36494695 http://dx.doi.org/10.1186/s12992-022-00898-2 |
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author | Omotoso, Olabode Ebenezer Teibo, John Oluwafemi Atiba, Festus Adebayo Oladimeji, Tolulope Adebesin, Ayomide Oluwadarasimi Babalghith, Ahmad O. |
author_facet | Omotoso, Olabode Ebenezer Teibo, John Oluwafemi Atiba, Festus Adebayo Oladimeji, Tolulope Adebesin, Ayomide Oluwadarasimi Babalghith, Ahmad O. |
author_sort | Omotoso, Olabode Ebenezer |
collection | PubMed |
description | This paper highlights the gap in the use of genomic data of Africans for global research efforts for disease cures. Genomic data represents an important tool used in disease research for understanding how diseases affect several populations and how these differences can be harnessed for the development of effective cures especially vaccines that have an impact at the genetic level e.g., RNA vaccines. This paper then provides a review of global genomic data status where three continents are reported to be the major contributor of genomic data to repositories used for disease research and the development of vaccines and medicines around the world. We reviewed the most recently published information about genetic data inclusiveness of populations, explaining how genomic data of Africans is lacking in global research efforts that cater towards the eradication of pandemics via the development of vaccines and other cures. We also discuss the implication of this non-inclusiveness for global disease burdens and indicate where changes need to be made in the last part of the paper. Lastly, the entire centers on some general policy recommendations to fully include African genomic data in such global genetic repositories. These recommendations can be implemented in African countries to improve genetic data collection, storage, and usage policies. |
format | Online Article Text |
id | pubmed-9733397 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-97333972022-12-10 Bridging the genomic data gap in Africa: implications for global disease burdens Omotoso, Olabode Ebenezer Teibo, John Oluwafemi Atiba, Festus Adebayo Oladimeji, Tolulope Adebesin, Ayomide Oluwadarasimi Babalghith, Ahmad O. Global Health Review This paper highlights the gap in the use of genomic data of Africans for global research efforts for disease cures. Genomic data represents an important tool used in disease research for understanding how diseases affect several populations and how these differences can be harnessed for the development of effective cures especially vaccines that have an impact at the genetic level e.g., RNA vaccines. This paper then provides a review of global genomic data status where three continents are reported to be the major contributor of genomic data to repositories used for disease research and the development of vaccines and medicines around the world. We reviewed the most recently published information about genetic data inclusiveness of populations, explaining how genomic data of Africans is lacking in global research efforts that cater towards the eradication of pandemics via the development of vaccines and other cures. We also discuss the implication of this non-inclusiveness for global disease burdens and indicate where changes need to be made in the last part of the paper. Lastly, the entire centers on some general policy recommendations to fully include African genomic data in such global genetic repositories. These recommendations can be implemented in African countries to improve genetic data collection, storage, and usage policies. BioMed Central 2022-12-09 /pmc/articles/PMC9733397/ /pubmed/36494695 http://dx.doi.org/10.1186/s12992-022-00898-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Review Omotoso, Olabode Ebenezer Teibo, John Oluwafemi Atiba, Festus Adebayo Oladimeji, Tolulope Adebesin, Ayomide Oluwadarasimi Babalghith, Ahmad O. Bridging the genomic data gap in Africa: implications for global disease burdens |
title | Bridging the genomic data gap in Africa: implications for global disease burdens |
title_full | Bridging the genomic data gap in Africa: implications for global disease burdens |
title_fullStr | Bridging the genomic data gap in Africa: implications for global disease burdens |
title_full_unstemmed | Bridging the genomic data gap in Africa: implications for global disease burdens |
title_short | Bridging the genomic data gap in Africa: implications for global disease burdens |
title_sort | bridging the genomic data gap in africa: implications for global disease burdens |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733397/ https://www.ncbi.nlm.nih.gov/pubmed/36494695 http://dx.doi.org/10.1186/s12992-022-00898-2 |
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