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Bridging the genomic data gap in Africa: implications for global disease burdens

This paper highlights the gap in the use of genomic data of Africans for global research efforts for disease cures. Genomic data represents an important tool used in disease research for understanding how diseases affect several populations and how these differences can be harnessed for the developm...

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Autores principales: Omotoso, Olabode Ebenezer, Teibo, John Oluwafemi, Atiba, Festus Adebayo, Oladimeji, Tolulope, Adebesin, Ayomide Oluwadarasimi, Babalghith, Ahmad O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733397/
https://www.ncbi.nlm.nih.gov/pubmed/36494695
http://dx.doi.org/10.1186/s12992-022-00898-2
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author Omotoso, Olabode Ebenezer
Teibo, John Oluwafemi
Atiba, Festus Adebayo
Oladimeji, Tolulope
Adebesin, Ayomide Oluwadarasimi
Babalghith, Ahmad O.
author_facet Omotoso, Olabode Ebenezer
Teibo, John Oluwafemi
Atiba, Festus Adebayo
Oladimeji, Tolulope
Adebesin, Ayomide Oluwadarasimi
Babalghith, Ahmad O.
author_sort Omotoso, Olabode Ebenezer
collection PubMed
description This paper highlights the gap in the use of genomic data of Africans for global research efforts for disease cures. Genomic data represents an important tool used in disease research for understanding how diseases affect several populations and how these differences can be harnessed for the development of effective cures especially vaccines that have an impact at the genetic level e.g., RNA vaccines. This paper then provides a review of global genomic data status where three continents are reported to be the major contributor of genomic data to repositories used for disease research and the development of vaccines and medicines around the world. We reviewed the most recently published information about genetic data inclusiveness of populations, explaining how genomic data of Africans is lacking in global research efforts that cater towards the eradication of pandemics via the development of vaccines and other cures. We also discuss the implication of this non-inclusiveness for global disease burdens and indicate where changes need to be made in the last part of the paper. Lastly, the entire centers on some general policy recommendations to fully include African genomic data in such global genetic repositories. These recommendations can be implemented in African countries to improve genetic data collection, storage, and usage policies.
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spelling pubmed-97333972022-12-10 Bridging the genomic data gap in Africa: implications for global disease burdens Omotoso, Olabode Ebenezer Teibo, John Oluwafemi Atiba, Festus Adebayo Oladimeji, Tolulope Adebesin, Ayomide Oluwadarasimi Babalghith, Ahmad O. Global Health Review This paper highlights the gap in the use of genomic data of Africans for global research efforts for disease cures. Genomic data represents an important tool used in disease research for understanding how diseases affect several populations and how these differences can be harnessed for the development of effective cures especially vaccines that have an impact at the genetic level e.g., RNA vaccines. This paper then provides a review of global genomic data status where three continents are reported to be the major contributor of genomic data to repositories used for disease research and the development of vaccines and medicines around the world. We reviewed the most recently published information about genetic data inclusiveness of populations, explaining how genomic data of Africans is lacking in global research efforts that cater towards the eradication of pandemics via the development of vaccines and other cures. We also discuss the implication of this non-inclusiveness for global disease burdens and indicate where changes need to be made in the last part of the paper. Lastly, the entire centers on some general policy recommendations to fully include African genomic data in such global genetic repositories. These recommendations can be implemented in African countries to improve genetic data collection, storage, and usage policies. BioMed Central 2022-12-09 /pmc/articles/PMC9733397/ /pubmed/36494695 http://dx.doi.org/10.1186/s12992-022-00898-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Omotoso, Olabode Ebenezer
Teibo, John Oluwafemi
Atiba, Festus Adebayo
Oladimeji, Tolulope
Adebesin, Ayomide Oluwadarasimi
Babalghith, Ahmad O.
Bridging the genomic data gap in Africa: implications for global disease burdens
title Bridging the genomic data gap in Africa: implications for global disease burdens
title_full Bridging the genomic data gap in Africa: implications for global disease burdens
title_fullStr Bridging the genomic data gap in Africa: implications for global disease burdens
title_full_unstemmed Bridging the genomic data gap in Africa: implications for global disease burdens
title_short Bridging the genomic data gap in Africa: implications for global disease burdens
title_sort bridging the genomic data gap in africa: implications for global disease burdens
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733397/
https://www.ncbi.nlm.nih.gov/pubmed/36494695
http://dx.doi.org/10.1186/s12992-022-00898-2
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