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Extracellular vesicles carrying HIV-1 Nef induce long-term hyperreactivity of myeloid cells

A possible explanation for chronic inflammation in HIV-infected individuals treated with anti-retroviral therapy is hyperreactivity of myeloid cells due to a phenomenon called “trained immunity.” Here, we demonstrate that human monocyte-derived macrophages originating from monocytes initially treate...

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Detalles Bibliográficos
Autores principales: Dubrovsky, Larisa, Brichacek, Beda, Prashant, N.M., Pushkarsky, Tatiana, Mukhamedova, Nigora, Fleetwood, Andrew J., Xu, Yangsong, Dragoljevic, Dragana, Fitzgerald, Michael, Horvath, Anelia, Murphy, Andrew J., Sviridov, Dmitri, Bukrinsky, Michael I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733434/
https://www.ncbi.nlm.nih.gov/pubmed/36417867
http://dx.doi.org/10.1016/j.celrep.2022.111674