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Les cellulites orbitaires: approche diagnostique, thérapeutique et pronostique dans un centre de référence à Tunis, Tunisie (une étude rétrospective sur 109 cas)

Orbital cellulitis is a rare disease. Two anatomo-clinical forms can be distinguished: a preseptal “benign” form and a retroseptal “severe” form. The purpose of this study was to analyze the epidemiological, clinical, therapeutic and prognostic profile of orbital cellulitis in a third-line Hospital...

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Autores principales: Mekni, Manel, Sayadi, Jihene, Choura, Racem, Fekih, Achraf, Gouider, Dhouha, Rouatbi, Aicha, Zghal, Imene, Malek, Ines, Chebbi, Amel, Nacef, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733463/
https://www.ncbi.nlm.nih.gov/pubmed/36523283
http://dx.doi.org/10.11604/pamj.2022.43.64.34807
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author Mekni, Manel
Sayadi, Jihene
Choura, Racem
Fekih, Achraf
Gouider, Dhouha
Rouatbi, Aicha
Zghal, Imene
Malek, Ines
Chebbi, Amel
Nacef, Leila
author_facet Mekni, Manel
Sayadi, Jihene
Choura, Racem
Fekih, Achraf
Gouider, Dhouha
Rouatbi, Aicha
Zghal, Imene
Malek, Ines
Chebbi, Amel
Nacef, Leila
author_sort Mekni, Manel
collection PubMed
description Orbital cellulitis is a rare disease. Two anatomo-clinical forms can be distinguished: a preseptal “benign” form and a retroseptal “severe” form. The purpose of this study was to analyze the epidemiological, clinical, therapeutic and prognostic profile of orbital cellulitis in a third-line Hospital in Tunis, Tunisia. We conducted a retrospective study involving 109 patients hospitalized for orbital cellulitis. Two groups were distinguished: the retroseptal cellulitis group including 42 patients (38.5%) and the preseptal cellulitis group including 67 patients (61.5%). The average age of patients was 27.1 ± 34.8 years. The sex ratio M/F was 0.84 (45.9% of male patients). Acute sinusitis was the most frequently identified portal for retroseptal cellulitis entry (35.7%, n=15), while acute dacryocystitis was the most common cause of preseptal cellulitis (23.9%, n=16). Diabetes, non-functioning eye and prior use of non-steroidal anti-inflammatory drugs were associated with retroseptal cellulitis (p=0.007, p=0.022 and p=0.014 respectively). All patients received systemic antibiotic therapy. Ten patients (23.8%) of the retro-septal cellulitis group and 5 patients (7.46%) of the preseptal cellulitis group underwent surgery. Nine cases of blindness (8.2%), a case of septic shock and a case of death were reported. Poor prognostic factors were a time of consultation > 7 days (aOR = 4.277, 95% CI = 2.504-32.426, p = 0.006) and Chandler stage>III (aOR = 7.009, 95% CI = 1.69-51.839, p = 0.029). In developing countries and especially in Tunisia, orbital cellulitis can be sight threatening or even life-threatening. Early management could lead to a favorable outcome without sequelae.
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spelling pubmed-97334632022-12-14 Les cellulites orbitaires: approche diagnostique, thérapeutique et pronostique dans un centre de référence à Tunis, Tunisie (une étude rétrospective sur 109 cas) Mekni, Manel Sayadi, Jihene Choura, Racem Fekih, Achraf Gouider, Dhouha Rouatbi, Aicha Zghal, Imene Malek, Ines Chebbi, Amel Nacef, Leila Pan Afr Med J Case Series Orbital cellulitis is a rare disease. Two anatomo-clinical forms can be distinguished: a preseptal “benign” form and a retroseptal “severe” form. The purpose of this study was to analyze the epidemiological, clinical, therapeutic and prognostic profile of orbital cellulitis in a third-line Hospital in Tunis, Tunisia. We conducted a retrospective study involving 109 patients hospitalized for orbital cellulitis. Two groups were distinguished: the retroseptal cellulitis group including 42 patients (38.5%) and the preseptal cellulitis group including 67 patients (61.5%). The average age of patients was 27.1 ± 34.8 years. The sex ratio M/F was 0.84 (45.9% of male patients). Acute sinusitis was the most frequently identified portal for retroseptal cellulitis entry (35.7%, n=15), while acute dacryocystitis was the most common cause of preseptal cellulitis (23.9%, n=16). Diabetes, non-functioning eye and prior use of non-steroidal anti-inflammatory drugs were associated with retroseptal cellulitis (p=0.007, p=0.022 and p=0.014 respectively). All patients received systemic antibiotic therapy. Ten patients (23.8%) of the retro-septal cellulitis group and 5 patients (7.46%) of the preseptal cellulitis group underwent surgery. Nine cases of blindness (8.2%), a case of septic shock and a case of death were reported. Poor prognostic factors were a time of consultation > 7 days (aOR = 4.277, 95% CI = 2.504-32.426, p = 0.006) and Chandler stage>III (aOR = 7.009, 95% CI = 1.69-51.839, p = 0.029). In developing countries and especially in Tunisia, orbital cellulitis can be sight threatening or even life-threatening. Early management could lead to a favorable outcome without sequelae. The African Field Epidemiology Network 2022-10-07 /pmc/articles/PMC9733463/ /pubmed/36523283 http://dx.doi.org/10.11604/pamj.2022.43.64.34807 Text en Copyright: Manel Mekni et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Series
Mekni, Manel
Sayadi, Jihene
Choura, Racem
Fekih, Achraf
Gouider, Dhouha
Rouatbi, Aicha
Zghal, Imene
Malek, Ines
Chebbi, Amel
Nacef, Leila
Les cellulites orbitaires: approche diagnostique, thérapeutique et pronostique dans un centre de référence à Tunis, Tunisie (une étude rétrospective sur 109 cas)
title Les cellulites orbitaires: approche diagnostique, thérapeutique et pronostique dans un centre de référence à Tunis, Tunisie (une étude rétrospective sur 109 cas)
title_full Les cellulites orbitaires: approche diagnostique, thérapeutique et pronostique dans un centre de référence à Tunis, Tunisie (une étude rétrospective sur 109 cas)
title_fullStr Les cellulites orbitaires: approche diagnostique, thérapeutique et pronostique dans un centre de référence à Tunis, Tunisie (une étude rétrospective sur 109 cas)
title_full_unstemmed Les cellulites orbitaires: approche diagnostique, thérapeutique et pronostique dans un centre de référence à Tunis, Tunisie (une étude rétrospective sur 109 cas)
title_short Les cellulites orbitaires: approche diagnostique, thérapeutique et pronostique dans un centre de référence à Tunis, Tunisie (une étude rétrospective sur 109 cas)
title_sort les cellulites orbitaires: approche diagnostique, thérapeutique et pronostique dans un centre de référence à tunis, tunisie (une étude rétrospective sur 109 cas)
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733463/
https://www.ncbi.nlm.nih.gov/pubmed/36523283
http://dx.doi.org/10.11604/pamj.2022.43.64.34807
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