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Metformin in therapeutic applications in human diseases: its mechanism of action and clinical study
Metformin, a biguanide drug, is the most commonly used first-line medication for type 2 diabetes mellites due to its outstanding glucose-lowering ability. After oral administration of 1 g, metformin peaked plasma concentration of approximately 20–30 μM in 3 h, and then it mainly accumulated in the g...
Autores principales: | Du, Yang, Zhu, Ya-Juan, Zhou, Yi-Xin, Ding, Jing, Liu, Ji-Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733765/ https://www.ncbi.nlm.nih.gov/pubmed/36484892 http://dx.doi.org/10.1186/s43556-022-00108-w |
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