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Factors associated with non-response to naldemedine for opioid-induced constipation in cancer patients: A subgroup analysis

BACKGROUND: Opioid-induced constipation (OIC) is one of the most common adverse events of opioid therapy and can severely reduce quality of life (QOL). Naldemedine is the orally available peripheral-acting μ-opioid receptor antagonist approved for OIC treatment. However in daily clinical practice, s...

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Detalles Bibliográficos
Autores principales:	Kanbayashi, Yuko, Shimizu, Mayumi, Ishizuka, Yuichi, Sawa, Shohei, Yabe, Katsushige, Uchida, Mayako
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733844/ https://www.ncbi.nlm.nih.gov/pubmed/36490241 http://dx.doi.org/10.1371/journal.pone.0278823

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