Obeticholic acid treatment ameliorates the cardiac dysfunction in NASH mice

BACKGROUND: Suppression of cardiac iinflammasome, which can be inhibited by Farnesoid X receptor (FXR) agonist, can ameliorate cardiac inflammation and fibrosis. Increased cardiac inflammasome decrease the abundance of regulatory T (Treg) cells and exacerbate cardiac dysfunction. Interaction between...

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Detalles Bibliográficos
Autores principales: Liu, Szu-Yu, Huang, Chia-Chang, Yang, Ying-Ying, Huang, Shiang-Fen, Lee, Tzung-Yan, Li, Tzu-Hao, Hou, Ming-Chih, Lin, Han-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733885/
https://www.ncbi.nlm.nih.gov/pubmed/36490253
http://dx.doi.org/10.1371/journal.pone.0276717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733885/
https://www.ncbi.nlm.nih.gov/pubmed/36490253
http://dx.doi.org/10.1371/journal.pone.0276717

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