NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification

Hypoxia is a key characteristic of the breast cancer microenvironment that promotes expression of the transcriptional activator hypoxia-inducible factor 1 (HIF-1) and is associated with poor patient outcome. HIF-1 increases the expression or activity of stem cell pluripotency factors, which control...

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Detalles Bibliográficos
Autores principales: Yang, Yongkang, Chen, Chelsey, Zuo, Qiaozhu, Lu, Haiquan, Salman, Shaima, Lyu, Yajing, Huang, Tina Yi-Ting, Wicks, Elizabeth E., Jackson, Walter, Datan, Emmanuel, Wang, Ru, Wang, Yufeng, Le, Nguyet, Zhu, Yayun, Qin, Wenxin, Semenza, Gregg L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733926/
https://www.ncbi.nlm.nih.gov/pubmed/36490339
http://dx.doi.org/10.1126/sciadv.abo5000

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