WiChR, a highly potassium-selective channelrhodopsin for low-light one- and two-photon inhibition of excitable cells

The electric excitability of muscle, heart, and brain tissue relies on the precise interplay of Na(+)- and K(+)-selective ion channels. The involved ion fluxes are controlled in optogenetic studies using light-gated channelrhodopsins (ChRs). While non-selective cation-conducting ChRs are well establ...

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Detalles Bibliográficos
Autores principales: Vierock, Johannes, Peter, Enrico, Grimm, Christiane, Rozenberg, Andrey, Chen, I-Wen, Tillert, Linda, Castro Scalise, Alejandro G., Casini, Marilù, Augustin, Sandra, Tanese, Dimitrii, Forget, Benoît C., Peyronnet, Rémi, Schneider-Warme, Franziska, Emiliani, Valentina, Béjà, Oded, Hegemann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733931/
https://www.ncbi.nlm.nih.gov/pubmed/36383037
http://dx.doi.org/10.1126/sciadv.add7729

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