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Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro

SARS-CoV-2, a human coronavirus, is the causative agent of the COVID-19 pandemic. Its genome is translated into two large polyproteins subsequently cleaved by viral papain-like protease and main protease (Mpro). Polyprotein processing is essential yet incompletely understood. We studied Mpro-mediate...

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Detalles Bibliográficos
Autores principales:	Yadav, Ruchi, Courouble, Valentine V., Dey, Sanjay K., Harrison, Jerry Joe E. K., Timm, Jennifer, Hopkins, Jesse B., Slack, Ryan L., Sarafianos, Stefan G., Ruiz, Francesc X., Griffin, Patrick R., Arnold, Eddy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733933/ https://www.ncbi.nlm.nih.gov/pubmed/36490335 http://dx.doi.org/10.1126/sciadv.add2191

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