Identification of a novel GR-ARID1a-P53BP1 protein complex involved in DNA damage repair and cell cycle regulation

ARID1a (BAF250), a component of human SWI/SNF chromatin remodeling complexes, is frequently mutated across numerous cancers, and its loss of function has been putatively linked to glucocorticoid resistance. Here, we interrogate the impact of siRNA knockdown of ARID1a compared to a functional interfe...

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Detalles Bibliográficos
Autores principales: Stubbs, Felicity E., Flynn, Benjamin P., Rivers, Caroline A., Birnie, Matthew T., Herman, Andrew, Swinstead, Erin E., Baek, Songjoon, Fang, Hai, Temple, Jillian, Carroll, Jason S., Hager, Gordon L., Lightman, Stafford L., Conway-Campbell, Becky L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734058/
https://www.ncbi.nlm.nih.gov/pubmed/36344675
http://dx.doi.org/10.1038/s41388-022-02516-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734058/
https://www.ncbi.nlm.nih.gov/pubmed/36344675
http://dx.doi.org/10.1038/s41388-022-02516-2

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