Diethylcarbamazine, TRP channels and Ca(2+) signaling in cells of the Ascaris intestine

The nematode parasite intestine absorbs nutrients, is involved in innate immunity, can metabolize xenobiotics and as we show here, is also a site of action of the anthelmintic, diethylcarbamazine. Diethylcarbamazine (DEC) is used to treat lymphatic filariasis and activates TRP-2, GON-2 & CED-11...

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Detalles Bibliográficos
Autores principales: Williams, Paul D. E., Kashyap, Sudhanva S., McHugh, Mark A., Brewer, Matthew T., Robertson, Alan P., Martin, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734116/
https://www.ncbi.nlm.nih.gov/pubmed/36494409
http://dx.doi.org/10.1038/s41598-022-25648-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734116/
https://www.ncbi.nlm.nih.gov/pubmed/36494409
http://dx.doi.org/10.1038/s41598-022-25648-7

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