Cargando…
An efficient human stem cells derived cardiotoxicity testing platform for testing oncotherapeutic analogues of quercetin and cinnamic acid
Oncotherapeutics research is progressing at a rapid pace, however, not many drugs complete the successful clinical trial because of severe off-target toxicity to cardiomyocytes which ultimately leads to cardiac dysfunction. It is thus important to emphasize the need for early testing for possible ca...
Autores principales: | Mandal, Saurabh, Gamit, Naisarg, Biswas, Subhankar, Rao, C. Mallikarjun, Sethi, Gautam, Warrier, Sudha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734143/ https://www.ncbi.nlm.nih.gov/pubmed/36494370 http://dx.doi.org/10.1038/s41598-022-21721-3 |
Ejemplares similares
-
Identification of a Novel Wnt Antagonist Based Therapeutic and Diagnostic Target for Alzheimer’s Disease Using a Stem Cell-Derived Model
por: Patil, Manasi, et al.
Publicado: (2023) -
An Overview of Ovarian Cancer: The Role of Cancer Stem Cells in Chemoresistance and a Precision Medicine Approach Targeting the Wnt Pathway with the Antagonist sFRP4
por: Varier, Lavanya, et al.
Publicado: (2023) -
Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma
por: Bhuvanalakshmi, Gurubharathi, et al.
Publicado: (2018) -
Mechanistic Involvement of Long Non-Coding RNAs in Oncotherapeutics Resistance in Triple-Negative Breast Cancer
por: Kansara, Samarth, et al.
Publicado: (2020) -
Immuno-Oncotherapeutic Approaches in Advanced Hepatocellular Carcinoma
por: Park, Robin, et al.
Publicado: (2020)