Cargando…
Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors
Recent clinical development of KRAS inhibitors has heightened interest in the genomic landscape of KRAS-altered cancers. We performed a pan-cancer analysis of KRAS-altered samples from 426,706 adult patients with solid or hematologic malignancies using comprehensive genomic profiling; additional ana...
Autores principales: | Lee, Jessica K., Sivakumar, Smruthy, Schrock, Alexa B., Madison, Russell, Fabrizio, David, Gjoerup, Ole, Ross, Jeffrey S., Frampton, Garrett M., Napalkov, Pavel, Montesion, Meagan, Schutzman, Jennifer L., Ye, Xin, Hegde, Priti S., Nagasaka, Misako, Oxnard, Geoffrey R., Sokol, Ethan S., Ou, Sai-Hong Ignatius, Shi, Zhen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734185/ https://www.ncbi.nlm.nih.gov/pubmed/36494601 http://dx.doi.org/10.1038/s41698-022-00334-z |
Ejemplares similares
-
Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer
por: Sivakumar, Smruthy, et al.
Publicado: (2022) -
Biology and Targetability of the Extended Spectrum of PIK3CA Mutations Detected in Breast Carcinoma
por: Rugo, Hope S., et al.
Publicado: (2023) -
A pan-cancer landscape of telomeric content shows that RAD21 and HGF alterations are associated with longer telomeres
por: Sharaf, Radwa, et al.
Publicado: (2022) -
Characterization of Non–Small-Cell Lung Cancers With MET Exon 14 Skipping Alterations Detected in Tissue or Liquid: Clinicogenomics and Real-World Treatment Patterns
por: Lee, Jessica K., et al.
Publicado: (2021) -
The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA
por: Lee, Jessica K., et al.
Publicado: (2022)